Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D E, Salazar"'
Akademický článek
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Autor:
B T, Christian, E, Livni, J W, Babich, N M, Alpert, D D, Dischino, E, Ruediger, D E, Salazar, N F, Ford, A J, Fischman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 279(1)
BMS-181101 is a novel antidepressant drug that is currently under clinical investigation. The goal of this study was to evaluate the pharmacokinetics and receptor binding of this agent in the brains of healthy human volunteers. BMS-181101 was radiola
Publikováno v:
Pharmaceutical research. 12(11)
The absorption and disposition of nefazodone (NEF) and its metabolites hydroxynefazodone (HO-NEF), m-chlorophenylpiperazine (mCPP) and triazole dione (dione) were assessed in 10 healthy subjects following infusion of NEF solution into the proximal an
Publikováno v:
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 18(1)
Liver biopsies from 9 out of every 10 obese individuals exhibit pathological changes of unknown aetiology and 3 out of every 10 reflect severe injury in the form of periportal fibrosis. To examine the hypothesis that excessive fibrosis in obesity ari
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 20(3)
Obese human patients and obese overfed rats treated chronically with gentamicin suffer greater renal injury than nonobese patients and control animals. To understand the mechanism of this heightened susceptibility to the nephrotoxic effects of gentam
Publikováno v:
Molecular pharmacology. 39(3)
Cytochrome P450IIE1 (IIE1) is a microsomal xenobiotic-activating enzyme that is inducible not only by various chemical agents but also by fasting and diabetes. Using a rat model that mimics human obesity, we have found that hepatic IIE1 levels are al
Akademický článek
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Autor:
N. A. Farid, J. A. Jakubowski, C. D. Payne, Y. G. Li, Y. Jin, C. S. Ernest, K. J. Winters, J. T. Brandt, D. E. Salazar, D. S. Small
Publikováno v:
Current Medical Research & Opinion; Aug2009, Vol. 25 Issue 8, p1821-1829, 9p
Autor:
G B, Corcoran, D E, Salazar
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 16(6)
Publikováno v:
The American journal of medicine. 85(2)