Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D E, McCloskey"'
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(1)
The high levels of polyamines maintained in the prostate suggest that these compounds are important to prostate cell function and that disruption of polyamine metabolism may be an effective way to stop the growth of prostate cancer cells. The unsymme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e6e315103bed0a617953c3b6e34bcfc
https://pubmed.ncbi.nlm.nih.gov/10656427
https://pubmed.ncbi.nlm.nih.gov/10656427
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58f2bf76e3f9d3ea3461ccb464bbb1fb
https://pubmed.ncbi.nlm.nih.gov/9204159
https://pubmed.ncbi.nlm.nih.gov/9204159
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(5)
The ability of paclitaxel, one of the most active chemotherapeutic agents against breast cancer, to induce programmed cell death in hormone-independent MDA-MB-468 human breast cancer cells was assessed. Treatment of MDA-MB-468 cells led to growth inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caa2f296ff2eb4b91b1f8e94475fc13f
https://pubmed.ncbi.nlm.nih.gov/9816240
https://pubmed.ncbi.nlm.nih.gov/9816240
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 2(3)
The naturally occurring polyamines putrescine, spermidine, and spermine are required for cell growth. Based on this requirement, several polyamine analogues that interfere with polyamine function and metabolism have been synthesized as antineoplastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::393075fe75da4e548b7798a0069f1655
https://pubmed.ncbi.nlm.nih.gov/9816189
https://pubmed.ncbi.nlm.nih.gov/9816189
Publikováno v:
Recent progress in hormone research. 51
The need for improved systemic therapy for breast cancer is great. Cancer growth represents an imbalance between cell proliferation and cell death: thus, effective anti-cancer therapies may act to decrease cell proliferation or increase cell death, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e81bae09575d149fbf33f1e2250179d3
https://pubmed.ncbi.nlm.nih.gov/8701092
https://pubmed.ncbi.nlm.nih.gov/8701092
Publikováno v:
Cancer research. 55(15)
The need for antineoplastic compounds with novel mechanisms of action is great. One such agent is the recently synthesized polyamine analogue N1-ethyl-N11-((cyclopropyl)methyl)-4,8-diazaundecane (CPENSpm). Exposure of hormone-dependent and -independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24e7f940b83e56916e28aebdc96f8886
https://pubmed.ncbi.nlm.nih.gov/7614453
https://pubmed.ncbi.nlm.nih.gov/7614453
Publikováno v:
Leukemia. 7(12)
CCRF-CEM human leukemia sublines resistant to short-term methotrexate (MTX) exposure as a result of decreased folylpolyglutamate synthetase (FPGS) activity were examined for their response to other cytotoxic agents. The R3/7 and R30dm sublines displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::beddb6c2687484e6d521e85a1763d0ad
https://pubmed.ncbi.nlm.nih.gov/8255099
https://pubmed.ncbi.nlm.nih.gov/8255099
Publikováno v:
Advances in experimental medicine and biology. 338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e8dd29734a2e4a302e0c2e6ff870930
https://pubmed.ncbi.nlm.nih.gov/8304203
https://pubmed.ncbi.nlm.nih.gov/8304203
Publikováno v:
The Journal of biological chemistry. 266(10)
Determinants of methotrexate (MTX) resistance in cell lines resistant to short, but not continuous, MTX exposure were investigated since such lines may have relevance to clinical resistance. CCRF-CEM R30dm (R30dm), cloned from CCRF-CEM R30/6 (a MTX-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2665a3806e76d1d9c64601a515a4923e
https://pubmed.ncbi.nlm.nih.gov/2007575
https://pubmed.ncbi.nlm.nih.gov/2007575