Zobrazeno 1 - 10
of 172
pro vyhledávání: '"D E, Hughes"'
Autor:
Stuart H. Ralston, Karen Chapman, R. Graham G. Russell, D. E. Hughes, Lucien Aarden, Maxine Gowen, Abdul-Karim Al-Humidan
Publikováno v:
Journal of Bone and Mineral Research. 6:3-8
Recombinant human interleukin-6 (IL-6) was assessed for its ability to stimulate bone resorption in prelabeled mouse calvariae in vitro. IL-6 had no effect on bone resorption at concentrations ranging from 300 to 10,000 U/ml (3-1000 pg/ml). Neither t
Autor:
C. J. Bradley, D. E. Hughes
Publikováno v:
International Journal of Quantum Chemistry. 1:687-701
An investigation is made of the application of hypervirial relations to problems involving periodic potentials. Necessary and sufficient conditions are established for both diagonal and off-diagonal hypervirial relations to yield solutions of the Sch
Publikováno v:
Journal of Bone and Mineral Research. 20:1265-1274
Publikováno v:
European Radiology. 15:2194-2199
We retrospectively studied the frequency of persistent foci of fat signal on magnetic resonance (MR) imaging in osteomyelitis to assess its frequency, cause and diagnostic value. The radiographs and MR scans of 100 patients with a final diagnosis of
Publikováno v:
Gene Therapy. 8:568-578
In human cells, telomerase activity is regulated by transcriptional control of the telomerase reverse transcriptase gene (hTERT) whose product is the catalytic subunit of the enzyme. The hTERT promoter is active in virtually all types of tumors and i
Autor:
P. J. Masarachia, Steven P. Luckman, D. E. Hughes, Roslin Russell, A. A. Reszka, Gideon A. Rodan, J. M. Halasy, Michael J. Rogers, John E. Fisher, Gregg Wesolowski
Publikováno v:
Proceedings of the National Academy of Sciences. 96:133-138
Nitrogen-containing bisphosphonates were shown to cause macrophage apoptosis by inhibiting enzymes in the biosynthetic pathway leading from mevalonate to cholesterol. This study suggests that, in osteoclasts, geranylgeranyl diphosphate, the substrate
Publikováno v:
Journal of Bone and Mineral Research. 13:581-589
Bisphosphonates are currently the most important class of antiresorptive drugs used for the treatment of metabolic bone diseases. Although the molecular targets of bisphosphonates have not been identified, these compounds inhibit bone resorption by m
Autor:
D E Hughes, Brendan F. Boyce
Publikováno v:
Molecular Pathology. 50:132-137
Publikováno v:
Marine Biology. 128:39-48
Chlorophyll a, primary productivity and grazing by copepods on phytoplankton were measured in the upper water column during the summer of 1994/1995 at a coastal site near Davis Station, East Antarctica. Chlorophyll a was at a maximum in mid-December,
Publikováno v:
Microbial ecology. 11(1)
A total of 450 yeast isolates were obtained from up to 34 sites on 59 human subjects. The yeasts were characterized using morphological features and assimilation tests. Ten species were identified but, of these,Candida albicans andCandida parapsilosi