Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D E, Feierman"'
Autor:
D. E. Feierman
Publikováno v:
Acta Anaesthesiologica Scandinavica. 44:560-563
Background: Fentanyl is a synthetic opioid widely used in anesthesia and analgesia. In experimental animals and in humans it has been shown that most fentanyl biotransformation occurs in the liver, where this opioid is converted primarily to its N-de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3a6159ce3901239f4b8c03b904392e6
https://doi.org/10.1034/j.1399-6576.2000.00513.x
https://doi.org/10.1034/j.1399-6576.2000.00513.x
Autor:
D E, Feierman
Publikováno v:
Acta anaesthesiologica Scandinavica. 44(5)
Fentanyl is a synthetic opioid widely used in anesthesia and analgesia. In experimental animals and in humans it has been shown that most fentanyl biotransformation occurs in the liver, where this opioid is converted primarily to its N-dealkylated de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdb626085cb984d0897ea5bc685b729f
https://pubmed.ncbi.nlm.nih.gov/10786743
https://pubmed.ncbi.nlm.nih.gov/10786743
Autor:
D E, Feierman, Z, Melnikov
Publikováno v:
Alcoholism, clinical and experimental research. 21(9)
E-9 cells, a HepG2 cell line that has the alcohol-inducible human cytochrome P-4502E1 (CYP2E1) cloned into its genome, was tested for its ability to produce trifluoroacetyl (TFA) adducts from the metabolism of halothane. The metabolism of halothane r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::309d1856d69c06fbd6b956e05e2e75ee
https://pubmed.ncbi.nlm.nih.gov/9438519
https://pubmed.ncbi.nlm.nih.gov/9438519
Autor:
D E, Feierman, J M, Lasker
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 24(9)
The microsomal metabolism of fentanyl, a synthetic opioid commonly used in anesthesia, was investigated in human liver. Incubation of fentanyl with human hepatic microsomes fortified with NADPH resulted in the formation of a single major metabolite,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d2913ca3d225b2748230e9a39574e70
https://pubmed.ncbi.nlm.nih.gov/8886601
https://pubmed.ncbi.nlm.nih.gov/8886601
Autor:
D. E. Feierman, J. J. Mason
Publikováno v:
Anesthesiology. 81:A844
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00ccbeda8bff3967e88ebad7c614172d
https://doi.org/10.1097/00000542-199409001-00843
https://doi.org/10.1097/00000542-199409001-00843
Autor:
D. E. Feierman
Publikováno v:
The Journal of Trauma: Injury, Infection, and Critical Care. 35:328
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3fd335e914a6320158212e142a7efa
https://doi.org/10.1097/00005373-199308000-00069
https://doi.org/10.1097/00005373-199308000-00069
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 237(3)
Studies were carried out to characterize and compare the effects of pyrazole and 4-methylpyrazole, potent inhibitors of alcohol dehydrogenase, on microsomal oxidation of a variety of drugs and alcohols. Whereas pyrazole treatment of rats (200 mg/kg b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24311f671d3907a11f75911621042dd8
https://pubmed.ncbi.nlm.nih.gov/3712274
https://pubmed.ncbi.nlm.nih.gov/3712274
Publikováno v:
The Journal of biological chemistry. 263(2)
In vivo administration of the alcohol dehydrogenase inhibitor pyrazole induces a cytochrome P-450 isozyme. The pyrazole-inducible cytochrome P-450 has been purified from rat livers to electrophoretic homogeneity and its biochemical, spectral, and imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::174ea23b0bc522ec1018cb49a94a4143
https://pubmed.ncbi.nlm.nih.gov/3335529
https://pubmed.ncbi.nlm.nih.gov/3335529
Autor:
D E, Feierman, A I, Cederbaum
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(5)
Pyrazole and its analogues are widely used to inhibit alcohol dehydrogenase and to block the metabolism of ethanol. Experiments were conducted to demonstrate that pyrazole is oxidized to 4-hydroxypyrazole by isolated rat liver microsomes. A HPLC proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d895dd56acf0438f220aa121f6539aa7
https://pubmed.ncbi.nlm.nih.gov/2891479
https://pubmed.ncbi.nlm.nih.gov/2891479