Zobrazeno 1 - 10
of 42
pro vyhledávání: '"D E, Brenner"'
Autor:
D. E. Brenner
Publikováno v:
Hematology/Oncology Clinics of North America. 12:xi-xiii
Autor:
D E, Brenner
Publikováno v:
Current opinion in gastroenterology. 15(1)
Chemoprevention is defined as nutritional or pharmaceutical interventions designed to prevent or delay cellular transformation. Over the last year, the great excitement and interest in the mechanism, epidemiology, and preclinical and clinical chemopr
Autor:
D E, Brenner
Publikováno v:
Journal of cellular biochemistry. Supplement. 34
Cancer chemoprevention is a new discipline whose foundation rests upon epidemiologic evidence suggesting that dietary components such as beta-carotene, vitamin E, calcium and selenium may be inhibitors of carcinogenesis. Over the last decade, as mole
Publikováno v:
Primary care. 25(2)
Cancer chemoprevention uses noncytotoxic drugs or nutrients to prevent, retard, or delay carcinogenesis. The future of cancer chemoprevention depends on understanding key cellular growth and proliferation-controlling events, developing markers of mol
Publikováno v:
Journal of cellular biochemistry. Supplement.
We have studied aspirin as a potential chemopreventive for colorectal cancer, completing Phase I studies on aspirin pharmacology and potential biomarker assays (prostaglandins, PGE2 and PGF2 alpha and cyclooxygenase modulation) in normal human subjec
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 1(3)
Centrilobular hepatocyte contribution to doxorubicin (DOX) metabolism and myelotoxicity was probed with bromobenzene (BRB), a known centrilobular hepatotoxin. New Zealand White rabbits were given DOX, 3 mg/kg i.v. After 4 weeks, the rabbits were pret
Autor:
Walter A. Kukull, David Nochlin, Wayne C. McCormick, Meredith L. Pfanschmidt, James D. Bowen, D. E. Brenner, Eric B. Larson, Linda Teri, Carl E. Speck
Publikováno v:
Journal of the American Geriatrics Society. 42(7)
OBJECTIVE: To describe causes of death for patients with Alzheimer disease (AD) and other dementing illnesses enrolled in a population-based Alzheimer disease patient registry (ADPR) and to describe the variation in causes by the level of cognitive i
Autor:
D. E. Brenner
Publikováno v:
Annals of Oncology. 13:1697-1698
Autor:
J W, Cowens, P J, Creaven, W R, Greco, D E, Brenner, Y, Tung, M, Ostro, F, Pilkiewicz, R, Ginsberg, N, Petrelli
Publikováno v:
Cancer research. 53(12)
A liposome-encapsulated form of doxorubicin (TLC D-99), which was shown in preclinical toxicology to be less toxic to the gastrointestinal tract and myocardium than free doxorubicin, was administered by constant infusion (1.00-1.80 h) to 38 patients
Autor:
D E, Smith, D E, Brenner, C A, Knutsen, S J, Deremer, P A, Terrio, N J, Johnson, P L, Stetson, W D, Ensminger
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(2)
The pharmacokinetics of 5-fluorouracil (FUra) were studied alone and in the presence of either bromodeoxyuridine (BrdUrd) or iododeoxyuridine (IdUrd) in five mixed breed hounds. FUra was administered intravenously over 1 min as a 5 mg/kg dose in all