Zobrazeno 1 - 3
of 3
pro vyhledávání: '"D E, Beidler"'
Publikováno v:
The Journal of Immunology. 145:1200-1204
A simple method is described for the generation of a biologically produced mouse/human chimeric hetero-bifunctional antibody that has dual specificity for human carcinoembryonic Ag and metal chelate haptens. Two large compound chimeric vectors each c
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(4)
A simple method is described for the generation of a biologically produced mouse/human chimeric hetero-bifunctional antibody that has dual specificity for human carcinoembryonic Ag and metal chelate haptens. Two large compound chimeric vectors each c
Autor:
D L, Shawler, D E, Johnson, M D, Sweet, L J, Myers, S D, Tudor, D E, Beidler, J A, Koziol, R O, Dillman
Publikováno v:
Journal of biological response modifiers. 7(6)
We made an immunoconjugate (IC) using the anti-CD5 monoclonal antibody T101 and the chemotherapeutic drug methotrexate. Methotrexate was conjugated to T101 using an active ester intermediate, yielding a drug: antibody molar ratio of 12.4. Although T1