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Quantification of T-Cell Progenitors During Ontogeny: Thymus Colonization Depends on Blood Delivery of Progenitors

Autor: N. Allioli, O. Vainio, Christiane Ody, Beat A. Imhof, D. Dunon

Publikováno v: Blood. 93:2234-2243

An in vivo thymus reconstitution assay based on intrathymic injection of hematopoietic progenitors into irradiated chicks was used to determine the number of T-cell progenitors in peripheral blood, paraaortic foci, bone marrow (BM), and spleen during

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::048c7d1772df2bedaf8f27b33c0b06d9
https://doi.org/10.1182/blood.v93.7.2234

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Ontogeny of TCR V beta 1 expression revealed novel invariant alternative transcripts

Autor: D Dunon, J Schwager, J P Dangy, B A Imhof

Publikováno v: The Journal of Immunology. 154:1256-1264

Analysis of TCR-beta gene recombination and expression was performed by quantitative PCR amplification technique throughout chicken embryogenesis and development. Our data demonstrated that TCR V beta 1 promoters were turned on by day 10 of embryogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d8072d864db8b3dd8e9b666f8321e22
https://doi.org/10.4049/jimmunol.154.3.1256

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Mechanisms of thymus homing

Autor: BA Imhof, D Dunon

Publikováno v: Blood. 81:1-8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27207c20b1098401e2e0779a62da01a6
https://doi.org/10.1182/blood.v81.1.1.bloodjournal8111

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Core binding factor in the early avian embryo: cloning of Cbfbeta and combinatorial expression patterns with Runx1

Autor: Thierry Jaffredo, Karine Bollerot, D. Dunon, Stéphane Romero

Publikováno v: Gene expression patterns : GEP. 6(1)

We have isolated the avian ortholog for CBFbeta, the common non-DNA binding subunit of the core binding factor (CBF) that has important regulatory roles in major developmental pathways. CBFbeta forms heterodimers with the DNA-binding Runx proteins an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b585b3fb679b8a99d4f91318b422c88
https://pubmed.ncbi.nlm.nih.gov/16033710

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Intestinal CD8 alpha alpha and CD8 alpha beta intraepithelial lymphocytes are thymus derived and exhibit subtle differences in TCR beta repertoires

Autor: B A, Imhof, D, Dunon, D, Courtois, M, Luhtala, O, Vainio

Publikováno v: Journal of Immunology, Vol. 165, No 12 (2000) pp. 6716-6722

Intraepithelial lymphocytes (IEL) of the small intestine are anatomically positioned to be in the first line of cellular defense against enteric pathogens. Therefore, determining the origin of these cells has important implications for the mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::67fdd95a586c49d608f3283db291361a
https://archive-ouverte.unige.ch/unige:11327

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T Cell Migration During Ontogeny and T Cell Repertoire Generation

Autor: D. Dunon, Beat A. Imhof

Publikováno v: Current Topics in Microbiology and Immunology ISBN: 9783642800597

Before their hematopoietic stem cell origin was recognized, chicken thymocytes were thought to be derived from epithelial precursors in the thymus that could be converted into lymphocytes under the influence of surrounding mesenchymal tissue (Auerbac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c3efd7f573b3a9e8b25bd859b30c753
https://doi.org/10.1007/978-3-642-80057-3_8

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