Zobrazeno 1 - 10
of 103
pro vyhledávání: '"D Diedrich"'
Autor:
Kashi Raj Bhattarai, Robert J. Mobley, Kelly R. Barnett, Daniel C. Ferguson, Baranda S. Hansen, Jonathan D. Diedrich, Brennan P. Bergeron, Satoshi Yoshimura, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Defining genetic factors impacting chemotherapy failure can help to better predict response and identify drug resistance mechanisms. However, there is limited understanding of the contribution of inherited noncoding genetic variation on inte
Externí odkaz:
https://doaj.org/article/50de02b6348449e7a1264f8dc70d8016
Autor:
Xujie Zhao, Ping Wang, Jonathan D. Diedrich, Brandon Smart, Noemi Reyes, Satoshi Yoshimura, Jingliao Zhang, Wentao Yang, Kelly Barnett, Beisi Xu, Zhenhua Li, Xin Huang, Jiyang Yu, Kristine Crews, Allen Eng Juh Yeoh, Marina Konopleva, Chia-Lin Wei, Ching-Hon Pui, Daniel Savic, Jun J. Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Different molecular subtypes defined by specific gene rearrangements have been described for acute lymphoblastic leukaemia (ALL). Here, the authors show that ZNF384 fusion activates FLT3 expression conferring a therapeutic vulnerability for ZNF384- r
Externí odkaz:
https://doaj.org/article/d14b4f6c096c49f694347dc01d940e14
Autor:
Brennan P. Bergeron, Jonathan D. Diedrich, Yang Zhang, Kelly R. Barnett, Qian Dong, Daniel C. Ferguson, Robert J. Autry, Wenjian Yang, Baranda S. Hansen, Colton Smith, Kristine R. Crews, Yiping Fan, Ching-Hon Pui, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic
Publikováno v:
Leukemia. 36:2374-2383
Glucocorticoids (GCs) are a mainstay of contemporary, multidrug chemotherapy in the treatment of childhood acute lymphoblastic leukemia (ALL), and resistance to GCs remains a major clinical concern. Resistance to GCs is predictive of ALL relapse and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca26e5f075fcc38fa986e463ff324f89
https://doi.org/10.1038/s41375-022-01685-z
https://doi.org/10.1038/s41375-022-01685-z
Autor:
Izabela Podgorski, James Granneman, Elisabeth I. Heath, Seongho Kim, Krishna R. Maddipati, Carly Martin, Erandi Rajagurubandara, Jonathan D. Diedrich, Mackenzie K. Herroon
Figure S1: Production of eicosanoid species in tumor cell-adipocyte Transwell co-cultures and experimental bone tumors Figure S2. Bone marrow adipocyte numbers are increased in mice treated with Rosiglitazone (ROSI) and in genetically obese ob/ob mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aeb8078c20d78a48a60728afa860759
https://doi.org/10.1158/1541-7786.22512859.v1
https://doi.org/10.1158/1541-7786.22512859.v1
Autor:
Izabela Podgorski, James Granneman, Elisabeth I. Heath, Seongho Kim, Krishna R. Maddipati, Carly Martin, Erandi Rajagurubandara, Jonathan D. Diedrich, Mackenzie K. Herroon
Adipocyte–tumor cell cross-talk is one of the critical mediators of tumor progression and an emerging facilitator of therapy evasion. Tumor cells that metastasize to adipocyte-rich bone marrow take advantage of the interplay between metabolic and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c990f1747c15ede3dfdb661db97cf47
https://doi.org/10.1158/1541-7786.c.6540355.v1
https://doi.org/10.1158/1541-7786.c.6540355.v1
Akademický článek
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Autor:
Daniel C. Ferguson, J. Robert McCorkle, Kelly R. Barnett, Erik J. Bonten, Brennan P. Bergeron, Kashi Raj Bhattarai, Wenjian Yang, Colton Smith, Baranda S. Hansen, Richa Bajpai, Qian Dong, Robert J. Autry, Yoshihiro Gocho, Jonathan D. Diedrich, Kristine R. Crews, Shondra M. Pruett-Miller, Kathryn G. Roberts, Wendy Stock, Charles G. Mullighan, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Jun J. Yang, Mary V. Relling, William E. Evans, Daniel Savic
Publikováno v:
Blood Advances. 6:3386-3397
Understanding the genomic and epigenetic mechanisms of drug resistance in pediatric acute lymphoblastic leukemia (ALL) is critical for further improvements in treatment outcomes. The role of transcriptomic response in conferring resistance to l-aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03075279c797301a69a2f3fbe20a1aa3
https://doi.org/10.1182/bloodadvances.2022006965
https://doi.org/10.1182/bloodadvances.2022006965
Autor:
Kelly R. Barnett, Robert J. Mobley, Jonathan D. Diedrich, Brennan P. Bergeron, Kashi Raj Bhattarai, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Charles G. Mullighan, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
bioRxiv
SUMMARYB-cell lineage acute lymphoblastic leukemia (B-ALL) is comprised of diverse molecular subtypes and while transcriptional and DNA methylation profiling of B-ALL subtypes has been extensively examined, the accompanying chromatin landscape is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f213e6ffa6f24db72b8d17fd9ae7a235
https://doi.org/10.1101/2023.02.14.528493
https://doi.org/10.1101/2023.02.14.528493
Autor:
Kashi Raj Bhattarai, Robert J. Mobley, Kelly R. Barnett, Daniel C. Ferguson, Baranda S. Hansen, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Christopher S. Manring, Elias Jabbour, Elisabeth Paietta, Mark R. Litzow, Steven M. Kornblau, Wendy Stock, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, William E. Evans, Daniel Savic
Publikováno v:
medRxiv
Although acute lymphoblastic leukemia (ALL) is the most common childhood cancer, there is limited understanding of the contribution of inherited genetic variation on inter-individual differences in chemotherapy response. Defining genetic factors impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09ca0863c0f8c1cf5d3d98ce30a630
https://europepmc.org/articles/PMC9934807/
https://europepmc.org/articles/PMC9934807/
Akademický článek
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