Zobrazeno 1 - 10
of 98
pro vyhledávání: '"D Dafydd Jones"'
Autor:
Rebecca E. A. Gwyther, Sébastien Côté, Chang-Seuk Lee, Haosen Miao, Krithika Ramakrishnan, Matteo Palma, D. Dafydd Jones
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Carbon nanotube field effect transistors (CNT-FET) hold great promise as next generation miniaturised biosensors. One bottleneck is modelling how proteins, with their distinctive electrostatic surfaces, interact with the CNT-FET to modulate
Externí odkaz:
https://doaj.org/article/221203dc214c4534812fa833adfb5e30
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127504 (2015)
Expanded genetic code approaches are a powerful means to add new and useful chemistry to proteins at defined residues positions. One such use is the introduction of non-biological reactive chemical handles for site-specific biocompatible orthogonal c
Externí odkaz:
https://doaj.org/article/71c96f16787f478588106260ad200f47
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47132 (2012)
Enhanced Green Fluorescent Protein (EGFP) is one of the most widely used engineered variants of the original wild-type Green Fluorescent Protein. Here, we report the high resolution (1.35 Å) structure of EGFP crystallised in its untagged sequence fo
Externí odkaz:
https://doaj.org/article/bb916b0765784b6e8d9f0d99ac16af93
Autor:
D Dafydd Jones
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24319 (2011)
Combinatorial fragment exchange was utilised to recombine key structural and functional low homology regions of bacilli subtilisins to generate new active hybrid proteases with altered substrate profiles. Up to six different regions comprising mostly
Externí odkaz:
https://doaj.org/article/e7616f689c3e4f718af7ebea36fc00b3
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/95d820ea8ad54f09983daec782af34a7
Autor:
Nehad Noby, Husam Sabah Auhim, Samuel Winter, Harley L. Worthy, Amira M. Embaby, Hesham Saeed, Ahmed Hussein, Christopher R. Pudney, Pierre J. Rizkallah, Stephen A. Wells, D. Dafydd Jones
Publikováno v:
Open Biology, Vol 11, Iss 12 (2021)
Here we determined the structure of a cold active family IV esterase (EstN7) cloned from Bacillus cohnii strain N1. EstN7 is a dimer with a classical α/β hydrolase fold. It has an acidic surface that is thought to play a role in cold-adaption by re
Externí odkaz:
https://doaj.org/article/742a9bfe43b248879d57a96a80adc331
Autor:
Rachel L. Johnson, Hayley G. Blaber, Tomas Evans, Harley L. Worthy, Jacob R. Pope, D. Dafydd Jones
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The formation of protein complexes is central to biology, with oligomeric proteins more prevalent than monomers. The coupling of functionally and even structurally distinct protein units can lead to new functional properties not accessible by monomer
Externí odkaz:
https://doaj.org/article/5fc1cc52946046d5a53248b0cc84651c
Autor:
Jacob R. Pope, Rachel L. Johnson, W. David Jamieson, Harley L. Worthy, Senthilkumar Kailasam, Rochelle D. Ahmed, Ismail Taban, Husam Sabah Auhim, Daniel W. Watkins, Pierre J. Rizkallah, Oliver K. Castell, D. Dafydd Jones
Publikováno v:
Advanced Science, Vol 8, Iss 1, Pp n/a-n/a (2021)
Abstract Fluorescent proteins (FPs) are commonly used in pairs to monitor dynamic biomolecular events through changes in proximity via distance dependent processes such as Förster resonance energy transfer (FRET). The impact of FP association is ass
Externí odkaz:
https://doaj.org/article/7938b9fd96124ed0a636bbaf8e40a461
Autor:
Krithika Ramakrishnan, Rachel L. Johnson, Samuel D. Winter, Harley L. Worthy, Christopher Thomas, Diana C. Humer, Oliver Spadiut, Sarah H. Hindson, Stephen Wells, Andrew H. Barratt, Georgina E. Menzies, Christopher R. Pudney, D. Dafydd Jones
Publikováno v:
The FEBS Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d0f7078b1bc8d523de91505d2e4a37
https://doi.org/10.1111/febs.16783
https://doi.org/10.1111/febs.16783
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 955 (2021)
Here, we report the controlled assembly of SWCNT–GFP hybrids employing DNA as a linker. Two distinct, enriched SWCNTs chiralities, (6,5), (7,6), and an unsorted SWCNT solution, were selectively functionalized with DNA and hybridized to a complement
Externí odkaz:
https://doaj.org/article/aa247868891e42dbb0384c2bf1770d39