Zobrazeno 1 - 10
of 45
pro vyhledávání: '"D D Sedmak"'
Publikováno v:
The Journal of Immunology. 157:3317-3322
The IgG transporter responsible for ferrying maternal IgG across the human placenta to fetal circulation has not been identified, although the human homologue of the neonatal rat Fc receptor (FcRn), a heterodimer with pH-dependent IgG affinity, struc
Publikováno v:
The Journal of Immunology. 149:2473-2481
The microvascular endothelia of rejecting DBA/2----C57B1/6 murine cardiac allografts develop reactivity with the mAb M/K-2, which recognizes the murine homologue of the human leukocyte adhesion molecule VCAM-1. This reactivity does not develop in DBA
Publikováno v:
The Journal of Immunology. 148:3753-3760
To determine the relative ability of allogeneic endothelial cells to stimulate helper T lymphocytes (HTL), human PBMC or purified T cells were incubated in conventional lymphocyte microcultures or in limiting dilution microcultures with allogeneic hu
Publikováno v:
Blood. 75:1583-1586
Serum immunoglobulin (Ig) G subclass levels were measured in a radial immunodiffusion assay in 25 leukemic patients before and after allogenic bone marrow transplantation. All patients received a conditioning regimen of busulfan and cyclophosphamide
Publikováno v:
Current topics in microbiology and immunology. 269
Pathogens have evolved diverse mechanisms for escaping host innate and adaptive immunity. Viruses that maintain a persistent infection are particularly effective at disabling key arms of the host immune response. For example, the herpesviruses establ
Publikováno v:
Transplantation. 69(6)
Cytomegalovirus (CMV) is the primary viral cause of complications in transplant recipients. We sought to understand the mechanisms of its dissemination and induction of vascular disease, which may lead to transplant complications. Sialyl Lewis(x) (sL
Publikováno v:
Transplantation. 69(3)
Intercellular adhesion molecule-1 (ICAM-1) is strongly induced under inflammatory conditions associated with allograft rejection, thereby promoting leukocyte recruitment and activation at the site of inflammation. Enhancement of ICAM-1 expression can
Publikováno v:
Transplantation. 68(6)
Despite progress in antiviral chemotherapy, cytomegalovirus (CMV) remains a major cause of morbidity and mortality among pharmacologically immunosuppressed organ transplant recipients, frequently engaging the clinician in a struggle to balance graft
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(10)
The type I IFNs represent a primordial, tightly regulated defense system against acute viral infection. IFN-alpha confers resistance to viral infection by activating a conserved signal transduction pathway that up-regulates direct antiviral effectors
Autor:
F G, Cosio, R P, Pelletier, D D, Sedmak, M E, Falkenhain, M L, Henry, E A, Elkhammas, E A, Davies, G L, Bumgardner, R M, Ferguson
Publikováno v:
Transplantation. 67(5)
After transplantation renal allografts frequently develop interstitial fibrosis and tubular atrophy, and these pathologic changes are the hallmarks of chronic allograft nephropathy (CN). However, the diagnosis of CN has no specific pathogenic implica