Zobrazeno 1 - 10
of 19
pro vyhledávání: '"D D Schoof"'
Autor:
Hong Li, Peter S. Goedegebuure, Timothy J. Eberlein, D. D. Schoof, L. M. Douville, M. Scavone, G. C. Richmond
Publikováno v:
Journal of Clinical Oncology. 13:1939-1949
PURPOSE The objective of this study was to determine the tolerance and effect of moderate-dose recombinant human interleukin-2 (rHu IL-2) and tumor-infiltrating lymphocytes (TIL) in patients with metastatic melanoma (MM) or renal cell carcinoma (RCC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341235fc9590f4999c3ef2459fc918bd
https://doi.org/10.1200/jco.1995.13.8.1939
https://doi.org/10.1200/jco.1995.13.8.1939
Publikováno v:
The Journal of Immunology. 151:5472-5480
The interaction between T lymphocytes and the Ag-HLA complex on tumor cells is mediated by the TCR. The diversity and the specificity of the TCR are in part secondary to the gene rearrangement of the V region on the beta-chain (V beta). To determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd93ee0e3a5c4c28624a4939c0569e7b
https://doi.org/10.4049/jimmunol.151.10.5472
https://doi.org/10.4049/jimmunol.151.10.5472
Publikováno v:
The Journal of Immunology. 151:5481-5491
Tumor-associated lymphocytes (TAL) from the malignant ascites and tumor-infiltrating lymphocytes (TIL) from the solid tumor were isolated from six consecutive untreated ovarian cancer patients. Tumor-specific CTL were generated from both TAL and TIL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f75d9844be476a183483e6fa0ef3724
https://doi.org/10.4049/jimmunol.151.10.5481
https://doi.org/10.4049/jimmunol.151.10.5481
Autor:
D D, Schoof, J W, Smith, M L, Disis, P, Brant-Zawadski, W, Wood, T, Doran, E, Johnson, W J, Urba
Publikováno v:
Advances in experimental medicine and biology. 451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::193064ed2b5571f03cb0b160ed8ccc4e
https://pubmed.ncbi.nlm.nih.gov/10026920
https://pubmed.ncbi.nlm.nih.gov/10026920
Publikováno v:
International journal of cancer. 78(1)
We examined signaling molecules of peripheral blood T lymphocytes obtained from women with breast cancer. In 6 of 14 patients, T lymphocytes displayed an impaired ability to translocate NFêB p65 (Rel-A) following activation by anti-CD3 and IL-2. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f56bb6373334dc8bb1820619405c34db
https://pubmed.ncbi.nlm.nih.gov/9724088
https://pubmed.ncbi.nlm.nih.gov/9724088
Publikováno v:
Surgery. 114(2)
The existence of a tumor-specific T-cell immune response to human malignant melanoma has been well documented. In contrast, the existence of tumor-specific cytotoxic T lymphocyte to ovarian cancer remains controversial despite the abundant lymphocyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b7ab949366fec56495fcbbc197cf866
https://pubmed.ncbi.nlm.nih.gov/8342128
https://pubmed.ncbi.nlm.nih.gov/8342128
Publikováno v:
Surgery. 110(3)
Lymphokines, the soluble molecules produced by cells of the immune system, regulate cell-cell interactions and, consequently, the functional status of the immune system. Altering immunoregulatory pathways with lymphokines in vivo may provide a mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::914b4ad3c4cb2f843502b47d2ae792ca
https://pubmed.ncbi.nlm.nih.gov/1887370
https://pubmed.ncbi.nlm.nih.gov/1887370
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 65(1)
While developing an animal model of a vascular malformation, we found that two doses of cyclosporin A significantly reduced the smooth muscle cell hyperplasia observed in vein-arterial interposition grafts in Sprague-Dawley rats. Therefore, we hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7db7e233509545f79812b26d87e99068
https://pubmed.ncbi.nlm.nih.gov/2072660
https://pubmed.ncbi.nlm.nih.gov/2072660
Autor:
T J, Eberlein, D D, Schoof
Publikováno v:
Comprehensive therapy. 17(1)
The arena of cellular immunotherapy is an emerging field of study. The field has strong foundations in numerous animal tumor models, which provide avenues of research for refinements in human immunotherapy. Experience from a number of research center
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d402237aa91efe1a487a83aad0c304f
https://pubmed.ncbi.nlm.nih.gov/2001612
https://pubmed.ncbi.nlm.nih.gov/2001612
Publikováno v:
Cancer research. 50(9)
Seventeen consecutive s.c. murine tumors, derived from a sarcoma and a colon adenocarcinoma, were cultured in the presence of recombinant interleukin 2 (rIL-2) for growth of tumor-infiltrating lymphocytes (TIL). Identical cultures were activated by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a5be9b7d7585cc528132bc0efb16be4
https://pubmed.ncbi.nlm.nih.gov/2139356
https://pubmed.ncbi.nlm.nih.gov/2139356