Zobrazeno 1 - 10
of 251
pro vyhledávání: '"D D, Burton"'
Autor:
B S, Wong, A S, Rao, M, Camilleri, N, Manabe, S, McKinzie, I, Busciglio, D D, Burton, M, Ryks, A R, Zinsmeister
Publikováno v:
Alimentary pharmacologytherapeutics. 32(7)
The short-term effects of methylnaltrexone (MNTX), a peripherally acting mu-opioid receptor antagonist, on gastrointestinal and colonic transit remain unclear.To compare the effects of placebo, codeine, subcutaneous (s.c.) MNTX and codeine with s.c.
Publikováno v:
Alimentary pharmacologytherapeutics. 18(5)
To evaluate the effect of single administrations of asimadoline, a kappa-opioid agonist, on satiation volume, postprandial symptoms and gastric volumes.Healthy subjects received oral placebo, or 0.5 or 1.5 mg asimadoline in a randomized, double-blind
Autor:
H J, Kim, M, Camilleri, S, McKinzie, M B, Lempke, D D, Burton, G M, Thomforde, A R, Zinsmeister
Publikováno v:
Alimentary pharmacologytherapeutics. 17(7)
To investigate the effects of a probiotic formulation, VSL#3, on gastrointestinal transit and symptoms of patients with Rome II irritable bowel syndrome with predominant diarrhoea.Twenty-five patients with diarrhoea-predominant irritable bowel syndro
Autor:
E P, Bouras, S, Delgado-Aros, M, Camilleri, E J, Castillo, D D, Burton, G M, Thomforde, H J, Chial
Publikováno v:
Gut. 51(6)
Impaired gastric accommodation may lead to dyspeptic symptoms. A non-invasive method using single photon emission computed tomography (SPECT) has been developed to measure gastric volumes.Our aims were: to assess the accuracy of SPECT with three dime
Publikováno v:
Alimentary pharmacologytherapeutics. 16(10)
The intra- and inter-individual reproducibility of gastrointestinal and colonic transit tests require full characterization.(i) To characterize the normal values and reproducibility effects of age and gender on the scintigraphic transit of solids in
Publikováno v:
Alimentary pharmacologytherapeutics. 14(7)
Alosetron, a 5-HT3-receptor antagonist, relieves abdominal pain and improves bowel function in non-constipated, female patients with irritable bowel syndrome. 5-HT3 antagonists delay colonic transit, increase colonic compliance, and increase small in
Publikováno v:
Alimentary pharmacologytherapeutics. 14(6)
Visceral sensation and motility are important in functional gut disorders and are partly controlled by adrenergic innervation.To characterize the alpha2-adrenergic control of motor and sensory function of descending colon and rectum.In 32 healthy vol
Publikováno v:
Digestive diseases and sciences. 43(11)
We aimed to compare gastrointestinal transit and defecatory function in a random sample of people with or without diabetes mellitus in a US community who reported constipation or laxative use. In this pilot study we measured: gastric, small bowel, an
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 285(1)
The purpose of our study was to evaluate the effects of a new nonantibiotic motilide derived from erythromycin, EM574, on gastric emptying and to evaluate its safety. Thirty healthy volunteers received one of five oral doses of EM574 (5, 10, 20, 30 m
Autor:
S B, Saslow, M, Thumshirn, M, Camilleri, G R, Locke, G M, Thomforde, D D, Burton, R B, Hanson
Publikováno v:
Digestive diseases and sciences. 43(2)
The effect of H. pylori infection on gastric motility and sensation is unclear. Our hypothesis is that H. pylori infection increases gastric sensation and reduces gastric accommodation and emptying. In eight H. pylori-positive and eight H. pylori-neg