NCCIH Priorities for Natural Products Research

Autor: Patrick Still, Wen Chen, Wendy Weber, D. Craig Hopp

Publikováno v: Planta Medica. 88:698-701

The National Center for Complementary and Integrative Health (NCCIH) is the lead agency within the U. S. federal government for complementary and integrative health research, which includes natural products. Although NCCIH is one of the smaller compo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1b88f787fbc983092f41942542a9f4
https://doi.org/10.1055/a-1767-2226

Improving Natural Product Research Translation: from Source to Clinical Trial

Autor: Jacqueline M. Stephens, Barbara C. Sorkin, Mahtab Jafari, Paula N. Brown, Naomi K. Fukagawa, D. Craig Hopp, Mario G. Ferruzzi, Kathleen R. Pritchett-Corning, Jeffrey Paul, Hervé Tiriac, Daniel Lakens, Bruce Barrett, Floyd H. Chilton, Sara K. Quinney, Dan Xi, Barbara Rehermann, John B. MacMillan, Freddie Ann Hoffman, Nisha S. Sipes, David O. Meltzer, Christopher S. Coffey, Adam J. Kuszak, Frederic D. Bushman, Kenneth D.R. Setchell, D. Lansing Taylor, Gregory Bloss, Giovanna Zappalà, Marco Pahor, Michael A. Walters, Mairead Kiely, Steven J. Casper, Guido F. Pauli

Publikováno v: FASEB J
The FASEB Journal, 34(1), 41-65. FASEB
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, vol 34, iss 1

While great interest in health effects of natural product (NP) including dietary supplements and foods persists, promising preclinical NP research is not consistently translating into actionable clinical trial (CT) outcomes. Generally considered the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d69c2a017736fe5f583f3cc013b079
https://europepmc.org/articles/PMC7470648/

The Challenge of Reproducibility and Accuracy in Nutrition Research: Resources and Pitfalls

Autor: Adam J. Kuszak, D. Craig Hopp, Barbara C. Sorkin, John S. Williamson, Joseph M. Betz

Publikováno v: Advances in Nutrition. 7:383-389

Inconsistent and contradictory results from nutrition studies conducted by different investigators continue to emerge, in part because of the inherent variability of natural products, as well as the unknown and therefore uncontrolled variables in stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31659acb8f9a8446a4f2fab5154e8f0d
https://doi.org/10.3945/an.115.010595

Naturally complex: Perspectives and challenges associated with Botanical Dietary Supplement Safety assessment

Autor: Nigel J. Walker, Linda S. Birnbaum, Joseph M. Betz, D. Craig Hopp, Cynthia V. Rider, Paul M. Coates, Hellen Oketch-Rabah, John R. Bucher, Duffy MacKay, Kelly A. Shipkowski, Cara Welch

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 118

Due to the extensive use of botanical dietary supplements by consumers in the United States, there is a need for appropriate research and data to support safety assessments. Complexity and variability, both natural and introduced, of botanical dietar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28a6f03b5e96a6a90219f286d922d70
https://pubmed.ncbi.nlm.nih.gov/29626579

Citreamicins with Potent Gram-Positive Activity

Autor: Michele Luche, D Craig Hopp, Midori Clarke, Joshua Rhea, Dennis J. Milanowski, Khadidja Romari, Linda Francis, Ulla Mocek, Macarena Irigoyen, Daniel Jacobsen, Grant J Carr, Chris Smith, John Rabenstein

Publikováno v: Journal of Natural Products. 71:2032-2035

Two new xanthone antibiotics, citreamicin delta (1) and epsilon (2), with potent activity against Gram-positive pathogens including multidrug-resistant Staphylococcus aureus (MDRSA) were discovered. Compounds 1 and 2 exhibited MIC values < 1 microg/m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a10cc0189d6b78d1a186809c30c45d2
https://doi.org/10.1021/np800503z