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pro vyhledávání: '"D Clive"'
Autor:
James P. McKeown, Andrew J. Byrne, Sandra A. Bright, Clara E. Charleton, Shubhangi Kandwal, Ivan Čmelo, Brendan Twamley, Anthony M. McElligott, Darren Fayne, Niamh M. O’Boyle, D. Clive Williams, Mary J. Meegan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1034 (2024)
Chronic lymphocytic leukemia (CLL) is a malignancy of mature B cells, and it is the most frequent form of leukemia diagnosed in Western countries. It is characterized by the proliferation and accumulation of neoplastic B lymphocytes in the blood, lym
Externí odkaz:
https://doaj.org/article/ec8f4b69512c421787aea349de4351eb
Akademický článek
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Autor:
Andrew J. Byrne, Sandra A. Bright, James. P. McKeown, Adam Bergin, Brendan Twamley, Anthony M. McElligott, Sara Noorani, Shubhangi Kandwal, Darren Fayne, Niamh M. O’Boyle, D. Clive Williams, Mary J. Meegan
Publikováno v:
Molecules, Vol 28, Iss 24, p 8095 (2023)
Chronic lymphocytic leukaemia (CLL) is a malignancy of the immune B lymphocyte cells and is the most common leukaemia diagnosed in developed countries. In this paper, we report the synthesis and antiproliferative effects of a series of (E)-9-(2-nitro
Externí odkaz:
https://doaj.org/article/4eb2cf5d956c4622b0b26f06f0efdc53
Akademický článek
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Akademický článek
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Autor:
Kelly, Patrick M., Bright, Sandra A., Fayne, Darren, Pollock, Jade K., Zisterer, Daniela M., Williams, D. Clive, Meegan, Mary J.
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 September 2016 24(18):4075-4099
Autor:
Mark Lawler, Daniela M. Zisterer, D. Clive Williams, Elisabeth Vandenberghe, Mark A. Catherwood, Giuseppe Campiani, Stefania Butini, Paul V. Browne, Amjad Hayat, Siobhan McGuckin, Lisa M. Greene, Elaina N. Maginn, Anthony M. McElligott
Supplementary Figure Legend from The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ac8e5beb89534efc364ccf43606715
https://doi.org/10.1158/0008-5472.22379894.v1
https://doi.org/10.1158/0008-5472.22379894.v1
Autor:
Mark Lawler, Daniela M. Zisterer, D. Clive Williams, Elisabeth Vandenberghe, Mark A. Catherwood, Giuseppe Campiani, Stefania Butini, Paul V. Browne, Amjad Hayat, Siobhan McGuckin, Lisa M. Greene, Elaina N. Maginn, Anthony M. McElligott
Pyrrolo-1,5-benzoxazepine-15 (PBOX-15) is a novel microtubule depolymerization agent that induces cell cycle arrest and subsequent apoptosis in a number of cancer cell lines. Chronic lymphocytic leukemia (CLL) is characterized by clonal expansion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc490614fe6ca8eefef8c52349c98a22
https://doi.org/10.1158/0008-5472.c.6499382.v1
https://doi.org/10.1158/0008-5472.c.6499382.v1
Autor:
Mark Lawler, Daniela M. Zisterer, D. Clive Williams, Elisabeth Vandenberghe, Mark A. Catherwood, Giuseppe Campiani, Stefania Butini, Paul V. Browne, Amjad Hayat, Siobhan McGuckin, Lisa M. Greene, Elaina N. Maginn, Anthony M. McElligott
Supplementary Figure 1 from The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246cf98ac4163ac7a53578882209a326
https://doi.org/10.1158/0008-5472.22379897
https://doi.org/10.1158/0008-5472.22379897
Autor:
Páraic M. Keane, Clara Zehe, Fergus E. Poynton, Sandra A. Bright, Sandra Estayalo-Adrián, Stephen J. Devereux, Paul M. Donaldson, Igor V. Sazanovich, Michael Towrie, Stanley W. Botchway, Christine J. Cardin, D. Clive Williams, Thorfinnur Gunnlaugsson, Conor Long, John M. Kelly, Susan J. Quinn
Publikováno v:
Physical Chemistry Chemical Physics. 24:27524-27531
Time-resolved IR spectra of porphyrins bound to biomolecules are reported. DFT calculations aid porphyrin vibration assignment while distinctive IR bands reveal interactions with therapeutic targets such as quadruplex DNA and proteins in HeLa cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a0ee54e310a305a49a908f369ebd7f
https://doi.org/10.1039/d2cp04604k
https://doi.org/10.1039/d2cp04604k