Zobrazeno 1 - 10
of 40
pro vyhledávání: '"D C Roopenian"'
Autor:
G J Christianson, W Brooks, S Vekasi, E A Manolfi, J Niles, S L Roopenian, J B Roths, R Rothlein, D C Roopenian
Publikováno v:
The Journal of Immunology. 159:4781-4792
The goal of this study was to determine whether class I proteins play an important role in the regulation of Ig and to elucidate the mechanism(s) involved. We analyzed the phenotype imposed by a null allele of beta 2-microglobulin (beta 2m). Serum Ig
Autor:
W A Simmons, S G Summerfield, D C Roopenian, C A Slaughter, A R Zuberi, S J Gaskell, R S Bordoli, J Hoyes, C R Moomaw, R A Colbert, L Y Leong, G W Butcher, R E Hammer, J D Taurog
Publikováno v:
The Journal of Immunology. 159:2750-2759
We have identified two peptides corresponding to the male-specific HY minor histocompatibility Ags presented by HLA-B27 in transgenic rodents, isolated from whole cell extracts and from immunoprecipitated B27 molecules of male B27 rat spleen cells. H
Publikováno v:
The Journal of Immunology. 157:4421-4427
Splenic CD4+NK1.1+ T cells have been shown to secrete large and transient amounts of IL-4 mRNA 90 min after i.v. injection of anti-CD3 Ab, suggesting that this novel subset of T cells may induce Th2 responses in the spleen by quickly providing IL-4 a
Autor:
D. V. Serreze, W. S. Gallichan, D. P. Snider, K. Croitoru, K. L. Rosenthal, E. H. Leiter, G. J. Christianson, M. E. Dudley, D. C. Roopenian
Publikováno v:
Diabetes. 45:902-908
Autor:
G J Christianson, R L Blankenburg, T M Duffy, D Panka, J B Roths, A Marshak-Rothstein, D C Roopenian
Publikováno v:
The Journal of Immunology. 156:4932-4939
MRL-lpr/lpr mice develop a distinctive immunologic disease characterized by accumulation of unusually large numbers of T cells in the peripheral lymphoid organs. Most of the accumulating T cells express an alpha beta-TCR but are peculiar in that they
Publikováno v:
Oral microbiology and immunology. 14(3)
The purpose of this study was to determine whether humoral immunity prevents bacterially induced alveolar bone loss. BALB/cByJ mice were orally infected with the human periodontopathic bacterium Porphyromonas gingivalis, and were compared with sham-i
Autor:
H, Klinge, D C, Roopenian
Publikováno v:
Transplantation. 67(8)
The mammalian genome encodes numerous autosomal minor histocompatibilty (H) antigens that act as a barrier to allogeneic tissue transplantation when donor and recipient are matched for the major histocompatibilty complex (MHC). However, most of our u
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(8)
Of the many minor histocompatibility (H) Ags that have been detected in mice, the ability to induce graft vs host disease (GVHD) after bone marrow transplantation is restricted to a limited number of immunodominant Ags. One such murine Ag, B6dom1, is
Autor:
A, Boesteanu, M, Brehm, L M, Mylin, G J, Christianson, S S, Tevethia, D C, Roopenian, S, Joyce
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
CD8+ T cells respond to Ags when their clonotypic receptor, the TCR, recognizes nonself peptides displayed by MHC class I molecules. The TCR/ligand interactions are degenerate because, in its life time, the TCR interacts with self MHC class I-self pe
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(2)
The H3 complex, on mouse Chromosome 2, is an important model locus for understanding mechanisms underlying non-self Ag recognition during tissue transplantation rejection between MHC-matched mouse strains. H3a is a minor histocompatibility Ag gene, l