Multi-omic cross-sectional cohort study of pre-malignant Barrett’s esophagus reveals early structural variation and retrotransposon activity

Autor: A. C. Katz-Summercorn, S. Jammula, A. Frangou, I. Peneva, M. O’Donovan, M. Tripathi, S. Malhotra, M. di Pietro, S. Abbas, G. Devonshire, W. Januszewicz, A. Blasko, K. Nowicki-Osuch, S. MacRae, A. Northrop, A. M. Redmond, D. C. Wedge, R. C. Fitzgerald

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

The alterations associated with progression from Barrett’s esophagus (BE) to esophageal adenocarcinoma are not fully characterised. Here, the authors perform a multi-omics analysis of a longitudinally-sampled BE patient cohort, identifying the impa

Externí odkaz: https://doaj.org/article/f6679ac4c012459a94f788f21c46d6ba

Multi-omic cross-sectional cohort study of pre-malignant Barrett's esophagus reveals early structural variation and retrotransposon activity

Autor: A C, Katz-Summercorn, S, Jammula, A, Frangou, I, Peneva, M, O'Donovan, M, Tripathi, S, Malhotra, M, di Pietro, S, Abbas, G, Devonshire, W, Januszewicz, A, Blasko, K, Nowicki-Osuch, S, MacRae, A, Northrop, A M, Redmond, D C, Wedge, R C, Fitzgerald

Publikováno v: Nature communications. 13(1)

Barrett's esophagus is a pre-malignant lesion that can progress to esophageal adenocarcinoma. We perform a multi-omic analysis of pre-cancer samples from 146 patients with a range of outcomes, comprising 642 person years of follow-up. Whole genome se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::34bb9bd26bda81be7688b83183124bf1
https://pubmed.ncbi.nlm.nih.gov/35301290

Imaging-Based Efficacy Evaluation of Cancer Immunotherapy in Engineered Tumor Platforms and Tumor Organoids.

Autor: Kim SE; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, South Korea., Yun S; Interdisciplinary Program for Bioengineering, Seoul National University, Seoul, 08826, South Korea., Doh J; Interdisciplinary Program for Bioengineering, Seoul National University, Seoul, 08826, South Korea.; Department of Materials Science and Engineering, Research Institute of Advanced Materials, Institute of Engineering Research, Bio-MAX institute, Soft Foundry Institute, Seoul National University, Seoul, 08826, South Korea., Kim HN; Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, 02792, South Korea.; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul, 02792, Republic of Korea.; School of Mechanical Engineering, Yonsei University, Seoul, 03722, Republic of Korea.; Yonsei-KIST Convergence Research Institute, Yonsei University, Seoul, 03722, Republic of Korea.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Oct; Vol. 13 (27), pp. e2400475. Date of Electronic Publication: 2024 Jun 08.

Nanoplasmonic Single‐Tumoroid Microarray for Real‐Time Secretion Analysis.

Autor: Liu, Yen‐Cheng¹ (AUTHOR), Ansaryan, Saeid¹ (AUTHOR), Tan, Jiayi¹ (AUTHOR), Broguiere, Nicolas² (AUTHOR), Lorenzo‐Martín, Luis Francisco² (AUTHOR), Homicsko, Krisztian^3,4,5,6 (AUTHOR), Coukos, George^3,4,5,6 (AUTHOR), Lütolf, Matthias P.² (AUTHOR), Altug, Hatice¹ (AUTHOR) hatice.altug@epfl.ch

Publikováno v: Advanced Science. 9/11/2024, Vol. 11 Issue 34, p1-15. 15p.

Targeting Tumor Heterogeneity by Breaking a Stem Cell and Epithelial Niche Interaction Loop.

Autor: Ma, Rongze^1,2,3 (AUTHOR), Feng, Deyi^1,2 (AUTHOR), Chen, Jing⁴ (AUTHOR), Zhou, Jiecan^1,5 (AUTHOR), Xia, Kun^1,2 (AUTHOR), Kong, Xiangyin⁶ (AUTHOR), Hu, Guohong⁶ (AUTHOR), Lu, Pengfei^1,2,3 (AUTHOR) pengfei.lu@usc.edu.cn

Publikováno v: Advanced Science. 7/10/2024, Vol. 11 Issue 26, p1-19. 19p.