Zobrazeno 1 - 10
of 38
pro vyhledávání: '"D C, Rowlands"'
Autor:
D. C. Rowlands, Alan L. Parker, Shinichi Miyagawa, David J. Kerr, Fukuto Maruta, Jun Nakayama, Leonard W. Seymour, Noriyuki Akita, Tariq Ismail, Kerry D. Fisher
Intravenous targeting of anticancer agents should improve both efficacy and therapeutic index. However, rational design of targeting constructs requires detailed definition of receptor targets and must take account of polarised tissue architecture th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c155a0158f7d841d2187195070e355
https://ora.ox.ac.uk/objects/uuid:14a97e64-1174-44e1-9052-9c1b324ae63a
https://ora.ox.ac.uk/objects/uuid:14a97e64-1174-44e1-9052-9c1b324ae63a
Publikováno v:
Gastric Cancer. 2:226-229
BACKGROUND: Despite encouraging retrospective and non-randomized trials, two large prospective, randomized trials of D1 vs D2 resections show double the mortality in the D2 group, with no increase in long-term survival. However, the D2 resection stil
Publikováno v:
Molecular Pathology. 49:M273-M277
Aims-To overcome the problems associated with proteolytic pretreatment of tissue sections for the detection of apoptosis.Methods-Formalin fixed, paraffin wax embedded tissue sections of reactive lymph nodes and biopsy specimens of Burkitt lymphoma we
Publikováno v:
Thorax. 51:526-529
BACKGROUND: The multidrug resistance marker P-glycoprotein (P-gp) was studied immunohistochemically in 78 primary malignant lung tumours. P-gp is a 170 kD transmembrane ATP dependent drug efflux pump which has been shown to be important in the resist
Autor:
Philip J. Coates, R. Carl Hobbs, John Crocker, Paul Murray, D. C. Rowlands, Roy A. Quinlan, Peter A. Hall
Publikováno v:
The Journal of Pathology. 178:21-29
The murine monoclonal antibody BU31 binds to the nuclear membrane of many cell types. The expression of the BU31 antigen has previously been shown to have an inverse correlation with the proliferative index in lung tumours, defined by Ki67 staining.
Publikováno v:
Nephrology Dialysis Transplantation. 10:2212-2218
Background. Proliferating cells can be detected in histological material in various ways. This investigation was to study the feasibility and usefulness of application of proliferation markers to routine renal biopsy specimens. Methods. One hundred a
Publikováno v:
Molecular Pathology. 48:M88-M92
Aim —To determine the liver cell populations that express the phylogenetically conserved cytosolic protein stathmin during liver regeneration. Methods —Double immunostaining for stathmin and the Ki67 antigen was performed on sections of formaldeh
Autor:
D. C. Mangham, Lawrence S. Young, Hermann Herbst, K. M. Newbold, E. L. Jones, J. W. L. Fielding, Gary M. Reynolds, M Ito, D. C. Rowlands, M. T. Hallissey, Gerald Niedobitek
Publikováno v:
British Journal of Cancer
We have analysed 174 gastric carcinomas from the United Kingdom and from Japan for the presence of Epstein-Barr virus (EBV) using in situ hybridisation for the small EBV-encoded nuclear RNAs (EBERs). EBV was detected in the tumour cells in all of six
Publikováno v:
Hematological Oncology. 13:29-43
Lap 18 is a highly conserved cytosolic protein that is expressed in dividing cells. Data from a number of studies show that a range of cell lines and mitogen-stimulated normal cells cultured in PMA phosphorylate and subsequently down-regulate Lap 18.
Publikováno v:
Cytopathology. 5:345-358
Microwave oven antigen retrieval has been developed to extend the range of antibodies that can be used upon sections of fixed and processed tissue. It has the additional advantages of improving immunostain intensity and reducing background positivity