Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D C, Liotta"'
Publikováno v:
ChemInform. 25
Autor:
Donald J. Nelson, P A Furman, R E Dornsife, Lloyd Frick, D C Liotta, M T Paff, J A Wurster, James A. Fyfe, L J Wilson, Michelle G. Davis
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:2686-2692
The anti-hepatitis B (anti-HBV) activities of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine (2'-deoxy-3'-thia-5-fluorocytosine [FTC]) were studied by using an HBV-transfected cell line (HepG2 derivative
Autor:
R F, Schinazi, S J, Hurwitz, I, Liberman, A S, Juodawlkis, P, Tharnish, J, Shi, D C, Liotta, J A, Coderre, J, Olson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(2)
beta-5-o-Carboranyl-2'-deoxyuridine (D-CDU) is a nontoxic pyrimidine nucleoside analogue designed for boron neutron capture therapy of brain tumors. In vitro studies indicated that D-CDU accumulates to levels 92- and 117-fold higher than the extracel
Publikováno v:
Cancer research. 59(22)
Dietary sphingolipids inhibit chemically induced colon cancer in mice. The most likely mediators of this effect are the metabolites ceramide (Cer) and sphingosine, which induce growth arrest and apoptosis in transformed cells. Sphingolipids are diges
Autor:
A S, Bushnev, D C, Liotta
Publikováno v:
Methods in enzymology. 311
Autor:
H U, Humpf, E M, Schmelz, F I, Meredith, H, Vesper, T R, Vales, E, Wang, D S, Menaldino, D C, Liotta, A H, Merrill
Publikováno v:
The Journal of biological chemistry. 273(30)
Fumonisin B1 (FB1) is the predominant member of a family of mycotoxins produced by Fusarium moniliforme (Sheldon) and related fungi. Certain foods also contain the aminopentol backbone (AP1) that is formed upon base hydrolysis of the ester-linked tri
Publikováno v:
The Journal of biological chemistry. 272(30)
Interleukin 1beta (IL-1beta) induces the hydrolysis of sphingomyelin (SM) to ceramide (Cer) in primary cultures of rat hepatocytes, and Cer has been proposed to play a role in the down-regulation of cytochrome P450 2C11 (CYP2C11) and induction of alp
Autor:
A H, Merrill, E, Wang, T R, Vales, E R, Smith, J J, Schroeder, D S, Menaldino, C, Alexander, H M, Crane, J, Xia, D C, Liotta, F I, Meredith, R T, Riley
Publikováno v:
Advances in experimental medicine and biology. 392
Fumonisins are inhibitors of sphinganine (sphingosine) N-acyltransferase (ceramide synthase) in vitro, and exhibit competitive-type inhibition with respect to both substrates of this enzyme (sphinganine and fatty acyl-CoA). Removal of the tricarbally
Publikováno v:
The Journal of biological chemistry. 269(5)
Consumption of grains contaminated with Fusarium moniliforme (Sheldon) causes liver cancer in rats and has been correlated with esophageal cancer in humans. The causative agents are believed to be a family of compounds known as fumonisins, which bear
Autor:
Donald J. Nelson, L St John, L C Taylor, Furfine Eric Steven, G R Painter, P A Furman, Lloyd Frick, D C Liotta
Publikováno v:
Antimicrobial agents and chemotherapy. 37(11)
The pharmacokinetics and metabolism of the potent anti-human immunodeficiency virus and anti-hepatitis B virus compound, (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine (FTC), were investigated in male CD rats. Plasma clearance of