Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D C, Lehotay"'
Publikováno v:
Journal of Inherited Metabolic Disease. 27:81-88
Patients with medium-chain acyl-CoA dehydrogenase (MCAD) deficiency are unable to metabolize medium-chain fatty acids. Affected patients display a characteristic acylcarnitine profile when blood spots are collected after birth and analysed by tandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697e644f302745d437bb001884507f81
https://doi.org/10.1023/b:boli.0000016636.79030.ad
https://doi.org/10.1023/b:boli.0000016636.79030.ad
Publikováno v:
Journal of cardiac failure. 6(2)
Lipid peroxidation generates several unsaturated aldehydes, such as 4-OH-nonenal (HNE), which may interact with and modify the function of other molecules that are of biological importance. Although congestive heart failure (CHF) is a state of genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0075380c8aad5f491e919f938fe646e7
https://pubmed.ncbi.nlm.nih.gov/10908084
https://pubmed.ncbi.nlm.nih.gov/10908084
Autor:
Jacqueline M. Bourgeois, D. C. Lehotay, Xiaoping Luo, Brian H. Robinson, Sari Pitkänen, S. Bratinova, Sandeep Raha
Publikováno v:
Scopus-Elsevier
Complex I deficiency is perhaps the most common form of mitochondrial respiratory chain disease. We see more patient samples with this defect than any other. The variety of clinical phenotypes seen with complex I deficiency is continually expanding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7661b87dc0c3b70a4df63f992f0484
https://pubmed.ncbi.nlm.nih.gov/9568254
https://pubmed.ncbi.nlm.nih.gov/9568254
Publikováno v:
The Journal of nutrition. 126(11)
These studies examined the effect in rats of carnitine supplementation on variables of fat metabolism altered by administration of sodium pivalate, a compound which induces a carnitine deficiency. Weanling male rats received 20 mmol/L sodium pivalate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c72eb1e2b722bac78663b84d72ff816e
https://pubmed.ncbi.nlm.nih.gov/8914960
https://pubmed.ncbi.nlm.nih.gov/8914960
Autor:
D. C. Lehotay, B. E. P. Murphy
Publikováno v:
Endocrine Research Communications. 2:431-443
Plasma membranes were isolated from bovine renal cortex. This particulate, adenylate cyclase-containing fraction was stimulated to produce cyclic AMP by parathyroid hormone and fluoride. When the time-course of adenylate cyclase activity was investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f133676ce5daf164ee2c84d5f0b55fa7
https://doi.org/10.1080/07435807509084165
https://doi.org/10.1080/07435807509084165
Publikováno v:
Digestive Diseases and Sciences. 33:1454-1458
We have proposed that gastric peristaltic activity is primarily responsible for ulcerogenesis in the phenylbutazone-treated rat and that acid plays only a synergistic role. This study examines the effect of graded doses of the H2 blocker cimetidine o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf7a86864f9f1f8fa9b62d7c324ab20
https://doi.org/10.1007/bf01537002
https://doi.org/10.1007/bf01537002
Publikováno v:
Clinical Chemistry. 28:1826-1829
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467e2c62f67d61213af592763ac2c73b
https://doi.org/10.1093/clinchem/28.8.1826
https://doi.org/10.1093/clinchem/28.8.1826
Publikováno v:
Academic Medicine. 57:602-8
A decreasing number of physicians are selecting careers in clinical investigation. In order to aid in reversing this trend, the Physician Investigator Training Program for residents and postdoctoral fellows was developed within the Department of Medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb786ca07f18027a85ab5f2436eb970f
https://doi.org/10.1097/00001888-198208000-00004
https://doi.org/10.1097/00001888-198208000-00004
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 37(7)
Doxorubicin, an anthracycline antibiotic and antitumor agent, has cardiotoxic side-effects that limit its therapeutic usefulness. We have demonstrated that the drug inhibits cardiac guanylate cyclase activity in vitro. The biochemical changes followi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d37089b9b5551a00bb05f031c4c9e3b2
https://pubmed.ncbi.nlm.nih.gov/6141818
https://pubmed.ncbi.nlm.nih.gov/6141818
Publikováno v:
The New England journal of medicine. 305(15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8d5a928b3933c99f7dad2d061e0ce8b
https://pubmed.ncbi.nlm.nih.gov/7278888
https://pubmed.ncbi.nlm.nih.gov/7278888