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Autor:
C C, Felder, K E, Joyce, E M, Briley, M, Glass, K P, Mackie, K J, Fahey, G J, Cullinan, D C, Hunden, D W, Johnson, M O, Chaney, G A, Koppel, M, Brownstein
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 284(1)
LY320135 is a selective antagonist for the brain CB1 receptor, having greater than 70-fold higher affinity for the CB1 than the peripheral CB2 receptor. The Ki values for LY320135 at the CB1 and CB2 receptors, transfected and stably expressed in cell