Zobrazeno 1 - 10
of 11
pro vyhledávání: '"D C, Haines"'
Autor:
L. M. Anderson, J. M. Rice, L.K. Keefer, C.M. Maragos, C.L. Driver, B. A. Diwan, D. C. Haines, David A. Wink
Publikováno v:
Methods. 7:121-130
It is now well established that nitric oxide (NO) is both a critical bioregulatory agent essential to normal physiological function and a potentially toxic species. The primary goal of our NO research program is to investigate the possibility that ex
Publikováno v:
The FASEB Journal. 24
Autor:
Y H, Im, H T, Kim, I Y, Kim, V M, Factor, K B, Hahm, M, Anzano, J J, Jang, K, Flanders, D C, Haines, S S, Thorgeirsson, A, Sizeland, S J, Kim
Publikováno v:
Cancer research. 61(18)
The transforming growth factor-beta (TGF-beta) receptor complex and its downstream signaling intermediates constitute a tumor suppressor pathway. In many cancers, expression of TGF-beta type II receptor (TbetaR-II) is markedly decreased. In the prese
Autor:
Z, Zhang, B A, Diwan, L M, Anderson, D, Logsdon, O A, Olivero, D C, Haines, J M, Rice, S H, Yuspa, M C, Poirier
Publikováno v:
Molecular carcinogenesis. 23(1)
This study was designed to evaluate the potential initiating effects of transplacental 3'-azido-2',3'-dideoxythymine (AZT) and the role of ras mutational activation in skin tumors induced in a two-stage mouse skin model. In addition, mouse liver and
Publikováno v:
Cancer research. 57(24)
To test the hypothesis that the transforming growth factor-beta (TGF-beta) system has tumor suppressor activity in the mammary gland, we have generated transgenic mice overexpressing a dominant-negative mutant form of the type II TGF-beta receptor, u
Publikováno v:
Cancer research. 57(14)
We reported previously that calorie restriction (CR) delays spontaneous carcinogenesis in p53-deficient (p53-/-) mice, suggesting that CR modulates carcinogenesis by p53-independent mechanisms. To further evaluate the role of p53, we monitored tumor
Publikováno v:
Laboratory animal science. 46(1)
Large bowel disease detected clinically by rectal prolapse was studied in 64 immunodeficient mice (37 athymic NCr-nu/nu, 12 BALB/c AnNCr-nu/nu, 9 C57BL/6NCr-nu/nu, and 6 C.B17/Icr-scid/NCr) naturally infected with Helicobacter hepaticus. Rectal prola
Publikováno v:
Cancer research. 55(18)
Spontaneous tumorigenesis was evaluated in male p53-knockout (p53-/-) mice treated with dehydroepiandrosterone (DHEA), quercetin, d-limonene, or all-trans retinoic acid to determine whether tumor development in these mice can be modulated by cancer-c
Autor:
R J, Russell, D C, Haines, M R, Anver, J K, Battles, P L, Gorelick, L L, Blumenauer, M A, Gonda, J M, Ward
Publikováno v:
Laboratory animal science. 45(4)
The use of antibiotic combinations to prevent acute and progressive chronic hepatitis and proliferative typhlitis associated with Helicobacter hepaticus infection in male scid/NCr mice was evaluated. The drug combinations used were amoxicillin-metron
Publikováno v:
The American journal of pathology. 145(4)
Helicobacter infections cause chronic gastroenteritis in humans and several animal species. We recently discovered a new Helicobacter (H. hepaticus) that is the etiological agent of a unique chronic active hepatitis in mice. Natural infection appeare