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Evaluation of the anti-influenza virus activities of 1,3,4-thiadiazol-2-ylcyanamide (LY217896) and its sodium salt

Autor: J. Tang, Frantz Victor, Wayne A. Spitzer, C. Y. E. Wu, J. R. Nelson, Joseph M. Colacino, D. C. Delong

Publikováno v: Antimicrobial agents and chemotherapy. 34(11)

1,3,4-Thiadiazol-2-ylcyanamide (LY217896) and its sodium salt were shown to be effective against influenza A and B viruses in vitro and in the mouse model. In nondividing confluent MDCK cells, the 50% inhibitory concentration of LY217896 ranged from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e155f42883d7ee438fc2549da6520e58
https://pubmed.ncbi.nlm.nih.gov/2073106

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Controlled trial of enviroxime against natural rhinovirus infections in a community

Autor: E R Bryan, D C DeLong, F D Miller, A Exelby, Arnold S. Monto, S Srivastava

Publikováno v: Antimicrobial Agents and Chemotherapy. 27:102-106

The therapeutic effect of intranasally administered enviroxime was tested against naturally occurring common colds. The double-blind evaluation was carried out in Tecumseh, Mich., during a period when rhinoviruses are usually the principal pathogen.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5984f9e9e7c65ed55bef660a78b0fd8
https://doi.org/10.1128/aac.27.1.102

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Inability of anti-asialo-GM1 and 2-chloroadenosine to abrogate maleic anhydride-divinyl ether-induced resistance against experimental murine lung carcinoma metastases

Autor: R M, Schultz, J C, Tang, D C, DeLong, E W, Ades, M G, Altom

Publikováno v: Cancer research. 46(11)

Both macrophages and natural killer cells have been implicated in the antimetastatic activity of maleic anhydride-divinyl ether (MVE-5). In the present study, we attempted to utilize anti-asialo-GM1 antibody and 2-chloroadenosine, agents that kill na

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4a79875f43875e13a7fa9e470533ceb4
https://pubmed.ncbi.nlm.nih.gov/3756909

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