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Effect of recombinant granulocyte colony-stimulating factor on neutrophil kinetics in normal young and elderly humans

Autor: T H, Price, G S, Chatta, D C, Dale

Publikováno v: Blood. 88:335-340

Recombinant granulocyte colony-stimulating factor (G-CSF) was administered to healthy young (n = 32) and elderly (n = 19) volunteers (0 microgram/d, 30 microgram/d, or 300 microgram/d) to determine its effect on neutrophil production, blood kinetics,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb676e82a8967551e9097b803159da9a
https://doi.org/10.1182/blood.v88.1.335.335

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Spontaneous remission of granulocyte colony-stimulating factor–associated leukemia in a child with severe congenital neutropenia

Autor: Sima Jeha, A G Aprikyan, Kawah Chan, Steven J. Culbert, Maher Albitar, H Zietz, William K. Hoots, D C Dale

Publikováno v: Blood. 96:3647-3649

Leukemia is observed with increased frequency in patients with severe congenital neutropenia (SCN). In the past decade, recombinant human granulocyte colony-stimulating factor (rh G-CSF) has prolonged the survival of patients with SCN increasingly re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56a423b3c23c5dbf0435f743d96c8f42
https://doi.org/10.1182/blood.v96.10.3647.h8003647_3647_3649

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The benefits of haematopoietic growth factors in the management of gynaecological oncology

Autor: D C, Dale

Publikováno v: European journal of gynaecological oncology. 25(2)

Neutropenia and anemia are important complications of cancer chemotherapy and can be prevented and treated with granulocyte colony-stimulating factor and erythropoietin.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4239d86cdae70f2a1101aa599027d100
https://pubmed.ncbi.nlm.nih.gov/15032269

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The rate of apoptosis in post mitotic neutrophil precursors of normal and neutropenic humans

Autor: M C, Mackey, A A G, Aprikyan, D C, Dale

Publikováno v: Cell proliferation. 36(1)

Using data on the fraction of post‐mitotic neutrophil precursors (CD15(+) cells) displaying positive markers for apoptosis in 12 normal humans, and a simple mathematical model, we have estimated the apoptotic rate to be about 0.28/day in this compa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5904fe3f101da1c84b79e0bed630c492
https://pubmed.ncbi.nlm.nih.gov/12558658

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Spontaneous remission of granulocyte colony-stimulating factor-associated leukemia in a child with severe congenital neutropenia

Autor: S, Jeha, K W, Chan, A G, Aprikyan, W K, Hoots, S, Culbert, H, Zietz, D C, Dale, M, Albitar

Publikováno v: Blood. 96(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78ebd87aa06c8ac24a769086369df09e
https://pubmed.ncbi.nlm.nih.gov/11071667

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Mutations in the gene encoding neutrophil elastase in congenital and cyclic neutropenia

Autor: D C, Dale, R E, Person, A A, Bolyard, A G, Aprikyan, C, Bos, M A, Bonilla, L A, Boxer, G, Kannourakis, C, Zeidler, K, Welte, K F, Benson, M, Horwitz

Publikováno v: Blood. 96(7)

Congenital neutropenia and cyclic neutropenia are disorders of neutrophil production predisposing patients to recurrent bacterial infections. Recently the locus for autosomal dominant cyclic neutropenia was mapped to chromosome 19p13.3, and this dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e612d79bd2cebfcab65f77b26de8b84
https://pubmed.ncbi.nlm.nih.gov/11286224

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