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Autor: D C, Bloom

Publikováno v: Methods in molecular medicine. 10

A number of aspects of the natural biology of herpes simplex virus (HSV) make it an attractive candidate for a vector to express foreign genes within the nervous system. Some of the advantages of an HSV vector are 1 Establishment of a life-long laten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dec0690886a87fbd76ed803326dc8e14
https://pubmed.ncbi.nlm.nih.gov/21374242

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In vivo gene transfer to the brain cortex using a single injection of HSV-1 vector into the medial septum

Autor: S, Tabbaa, T D, Corso, L, Jenkins, R K, Tran, D C, Bloom, M K, Stachowiak

Publikováno v: Folia morphologica. 64(4)

This study shows that an ICP4-replication-deficient herpes simplex virus containing the Moloney murine leukaemia virus LTR fused with the coding sequence for the beta-galactosidase gene can be used as a very effective vector for delivering the beta-g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6411df2c37dbe9a6ec09af97eebcdc16
https://pubmed.ncbi.nlm.nih.gov/16425153

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Leiomyoma of the nasal septum

Autor: D C, Bloom, J C, Finley, T G, Broberg, R A, Cueva

Publikováno v: Rhinology. 39(4)

Leiomyoma is a benign myogenic tumor that may develop wherever smooth muscle is present. It occurs commonly in the uterus, skin, and gastrointestinal tract and is rare within the nasal cavity. Only three of twenty-four reported cases of sinonasal lei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9640dd5c3389953d3336382276684a8d
https://pubmed.ncbi.nlm.nih.gov/11826696

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Gene transfer into the central nervous system using herpes simplex virus-1 vectors

Autor: S, Tabbaa, C, Goulah, R K, Tran, A, Lis, R, Korody, B, Stachowski, J M, Horowitz, G, Torres, E K, Stachowiak, D C, Bloom, M K, Stachowiak

Publikováno v: Folia morphologica. 59(4)

Manipulation of gene expression in developing or in mature central nervous systems (CNS) holds a promise for the resolution of many compelling neurobiological questions, including the feasibility of gene therapy to treat diseases of the brain. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a13f5f4b02710588e81bc94f357a3076
https://pubmed.ncbi.nlm.nih.gov/11107692

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A 437-base-pair deletion at the beginning of the latency-associated transcript promoter significantly reduced adrenergically induced herpes simplex virus type 1 ocular reactivation in latently infected rabbits

Autor: Emily D. Varnell, Jeannette M. Loutsch, Y H Su, James M. Hill, L A Hanna, R Meegalla, T M Block, Hilary W. Thompson, H H Garza, D C Bloom

Publikováno v: Journal of virology. 71(9)

In this study we used a herpes simplex virus type 1 (HSV-1) deletion mutant to identify a segment of the genome necessary for epinephrine-induced reactivation in the rabbit eye model of herpetic recurrent disease. In HSV-1 latently infected neural ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be4207d07be778c8b176400dd1da73b
https://pubmed.ncbi.nlm.nih.gov/9261376

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Long-term expression of genes in vivo using non-replicating HSV vectors

Autor: D C, Bloom, J R, Lokensgard, N T, Maidment, L T, Feldman, J G, Stevens

Publikováno v: Gene therapy. 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e35bd4e3dd073e0e5c2195267b1a475
https://pubmed.ncbi.nlm.nih.gov/8542391

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