Zobrazeno 1 - 10
of 3 988
pro vyhledávání: '"D Berger"'
Autor:
Hannah L. Williams, Ana Leni Frei, Thibaud Koessler, Martin D. Berger, Heather Dawson, Olivier Michielin, Inti Zlobec
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract Enabling the examination of cell-cell relationships in tissue, spatially resolved omics technologies have revolutionised our perspectives on cancer biology. Clinically, the development of immune checkpoint inhibitors (ICI) has advanced cance
Externí odkaz:
https://doaj.org/article/f2ef085cd2a340bbb4523c525e173237
Autor:
Alisa Ambrodji, Angélique Sadlon, Ursula Amstutz, Dennis Hoch, Martin D. Berger, Sara Bastian, Steven M. Offer, Carlo R. Largiadèr
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7599 (2024)
Pre-treatment genotyping of four well-characterized toxicity risk-variants in the dihydropyrimidine dehydrogenase gene (DPYD) has been widely implemented in Europe to prevent serious adverse effects in cancer patients treated with fluoropyrimidines.
Externí odkaz:
https://doaj.org/article/ce0598a69e0643af8b35f34578e4afc4
Autor:
Kai Zimmer, Florian Kocher, Gerold Untergasser, Brigitte Kircher, Arno Amann, Yasmine Baca, Joanne Xiu, W. Micheal Korn, Martin D. Berger, Heinz-Josef Lenz, Alberto Puccini, Elisa Fontana, Anthony F. Shields, John L. Marshall, Michael Hall, Wafik S. El-Deiry, David Hsiehchen, Teresa Macarulla, Josep Tabernero, Renate Pichler, Moh’d Khushman, Upender Manne, Emil Lou, Dominik Wolf, Viktorija Sokolova, Simon Schnaiter, Alain G. Zeimet, Pat Gulhati, Gerlig Widmann, Andreas Seeber
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Polybromo-1 (PBRM1) loss of function mutations are present in a fraction of biliary tract cancers (BTCs). PBRM1, a subunit of the PBAF chromatin-remodeling complex, is involved in DNA damage repair. Herein, we aimed to decipher the molecular
Externí odkaz:
https://doaj.org/article/5241117531c4407f8106f8137c687dda
Autor:
Morin Beyeler, Pasquale Castigliego, Joel Baumann, Victor Ziegler, Moritz Kielkopf, Madlaine Mueller, Stefan A. Bauer-Gambelli, Adnan Mujanovic, Thomas Raphael Meinel, Thomas Horvath, Urs Fischer, Johannes Kaesmacher, Mirjam R. Heldner, David Seiffge, Marcel Arnold, Thomas Pabst, Martin D. Berger, Babak B. Navi, Simon Jung, Philipp Bücke
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and aimParaneoplastic coagulopathy can present as stroke and is associated with specific biomarker changes. Identifying paraneoplastic coagulopathy can help guide secondary prevention in stroke patients, and early cancer detection might im
Externí odkaz:
https://doaj.org/article/cf81aabdcb1b43988e9ee5f9eb13b587
Autor:
Luca Noti, José A. Galván, Heather Dawson, Alessandro Lugli, Richard Kirsch, Naziheh Assarzadegan, David Messenger, Philippe Krebs, Martin D. Berger, Inti Zlobec
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Previous assessments of peritumoral inflammatory infiltrate in colorectal cancer (CRC) have focused on the role of CD8+ T lymphocytes. We sought to compare the prognostic value of CD8 with downstream indicators of active immune ce
Externí odkaz:
https://doaj.org/article/cfbc8f10d8a7441da59d8e0291493ca3
Autor:
Emily K. Kleczko, Dustin T. Nguyen, Kenneth H. Marsh, Colin D. Bauer, Amy S. Li, Marie-Louise T. Monaghan, Michael D. Berger, Seth B. Furgeson, Berenice Y. Gitomer, Michel B. Chonchol, Eric T. Clambey, Kurt A. Zimmerman, Raphael A. Nemenoff, Katharina Hopp
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Innate and adaptive immune cells modulate the severity of autosomal dominant polycystic kidney disease (ADPKD), a common kidney disease with inadequate treatment options. ADPKD has parallels with cancer, in which immune checkpoint inhibitors have bee
Externí odkaz:
https://doaj.org/article/db0e24d1120a4e91b18a5137cdd01738
Autor:
Morin Beyeler, Lorenz Grunder, Jayan Göcmen, Fabienne Steinauer, Nebiyat F. Belachew, Moritz Kielkopf, Leander Clénin, Madlaine Mueller, Norbert Silimon, Christoph Kurmann, Thomas Meinel, Philipp Bücke, David Seiffge, Tomas Dobrocky, Eike I. Piechowiak, Sara Pilgram-Pastor, Heinrich P. Mattle, Babak B. Navi, Marcel Arnold, Urs Fischer, Thomas Pabst, Jan Gralla, Martin D. Berger, Simon Jung, Johannes Kaesmacher
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Background and aimIdentification of paraneoplastic hypercoagulability in stroke patients helps to guide investigations and prevent stroke recurrence. A previous study demonstrated an association between the absence of the susceptibility vessel sign (
Externí odkaz:
https://doaj.org/article/c93797984bad412aa4bd2cbe7ce886f3
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1411 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors, characterized by its aggressive tumor biology and poor prognosis. While immune checkpoint inhibitors (ICIs) play a major part in the treatment algorithm of various solid tumors,
Externí odkaz:
https://doaj.org/article/823c24020deb4467bb6c21998bc3ba97
Autor:
Alberto Puccini, Andreas Seeber, Joanne Xiu, Richard M. Goldberg, Davide Soldato, Axel Grothey, Anthony F. Shields, Mohamed E. Salem, Francesca Battaglin, Martin D. Berger, Wafik S. El-Deiry, Ryuma Tokunaga, Madiha Naseem, Wu Zhang, Sukeshi Patel Arora, Moh’d M. Khushman, Michael J. Hall, Philip A. Philip, John L. Marshall, W. Michael Korn, Heinz-Josef Lenz
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-8 (2021)
Abstract Lymph nodes (LNs) and distant metastases can arise from independent subclones of the primary tumor. Herein, we characterized the molecular landscape and the differences between LNs, distant metastases and primary colorectal cancers (CRCs). S
Externí odkaz:
https://doaj.org/article/c05cb963898a4501a8b4034e06807f08
Autor:
Nino Isakadze, Nancy Molello, Zane MacFarlane, Yumin Gao, Erin M Spaulding, Yvonne Commodore Mensah, Francoise A Marvel, Shireen Khoury, Joseph E Marine, Erin D Michos, David Spragg, Ronald D Berger, Hugh Calkins, Lisa A Cooper, Seth S Martin
Publikováno v:
JMIR Human Factors, Vol 9, Iss 4, p e38048 (2022)
BackgroundSmartphone ownership and mobile app use are steadily increasing in individuals of diverse racial and ethnic backgrounds living in the United States. Growing adoption of technology creates a perfect opportunity for digital health interventio
Externí odkaz:
https://doaj.org/article/09adb4dfa33d476dbe2162e2d799696c