Zobrazeno 1 - 10
of 41
pro vyhledávání: '"D B Maclean"'
Autor:
J. A. Nadel, J M Reis, John V. Fahy, D B Maclean, Hofer Wong, Homer A. Boushey, S C Harris, Pierangelo Geppetti
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 152:879-884
To investigate the role of NK1 receptors in the pathogenesis of bronchoconstriction and cough in asthma, we performed a randomized, double-blind, crossover study on the effects of a selective non-peptide tachykinin NK1 receptor antagonist (CP-99,994)
Autor:
Andrew G. Bostom, D B MacLean
Publikováno v:
New England Journal of Medicine. 326:705-708
Background. The effect of postmenopausal estrogen therapy on the risk of cardiovascular disease remains controversial. Our 1985 report in the Journal, based on four years of follow-up, suggested that estrogen therapy reduced the risk of coronary hear
Publikováno v:
Southern medical journal. 83(2)
The syndrome of inappropriate antidiuretic hormone secretion (SIADH) can result from diverse conditions. There have been only two published reports linking this syndrome with herpes zoster infections--one disseminated and the other confined to the ch
Autor:
D. B. MacLean
Publikováno v:
Diabetes. 36:390-395
Autor:
D. B. MacLean, N. E. Cundasawmy
Publikováno v:
Canadian Journal of Chemistry. 50:3028-3036
The spirobenzylisoquinoline system has been synthesized from substituted 2-phenyl-1,3-indandiones as starting materials. Ring B of the spiro system was constructed by a modified Pomeranz–Fritsch reaction. The reaction sequence has been applied to t
Autor:
D. B. MacLean, W. A. Harrison
Publikováno v:
Canadian Journal of Chemistry. 37:1757-1763
Information pertaining to the position of the carbonyl group relative to the nitrogen atom and to the size of one of the nitrogen rings in lycopodine has been obtained through a study of the reactions of α- and β-cyanobromolycopodine.
Publikováno v:
Canadian Journal of Chemistry. 47:3593-3599
The structures of fumaricine, fumaritine, and fumariline, minor alkaloids of F. officinalis, have been deduced by spectroscopic methods and by comparison with model systems. Nuclear Overhauser effects observed in these systems aided in the solution o
Autor:
D. B. MacLean, C.-Y. Chen
Publikováno v:
Canadian Journal of Chemistry. 45:3001-3004
Autor:
J. C. F. Young, D. B. MacLean
Publikováno v:
Canadian Journal of Chemistry. 41:2731-2736
A new alkaloid, C18H28ON2, designated flabelline, has been isolated by countercurrent distribution from the extract of Lycopodium flabelliforme. The structure and stereochemistry of flabelline have been established by its conversion to and preparatio
Publikováno v:
Canadian Journal of Chemistry. 38:528-538
A study has been made of the products formed on treatment of α- and β-cyanobromolycopodine with potassium hydroxide in methanol and potassium acetate in ethanol, respectively. The product derived from the α-isomer is apparently formed in a cycliza