Výsledky vyhledávání

Clinical presentation of primary progressive multiple sclerosis 10 years after the incidental finding of typical magnetic resonance imaging brain lesions

Autor: J. J. F. Oger, D. K. B. Li, G. V. Mcdonnell, D. B. Calne, J. Cabrera-Gomez

Publikováno v: Multiple Sclerosis Journal. 9:204-209

Background: Subclinical multiple sclerosis (MS) has been identified incidentally at autopsy; apparently unaffected individuals with an affected twin have demonstrated magnetic resonance imaging (MRI) changes consistent with MS, and ‘MRI relapses’

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7604ef6d4c8d9e6e3d3984617fcd7d
https://doi.org/10.1191/1352458503ms890cr

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Long term outcome of unilateral pallidotomy: follow up of 15 patients for 3 years

Autor: Ali Samii, D. B. Calne, Michael Schulzer, I M Turnbull, S Yardley, E Mak, Pramod Kumar Pal, Asha Kishore

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 69:337-344

OBJECTIVES—With the advent of new antiparkinsonian drug therapy and promising results from subthalamic and pallidal stimulation, this study evaluated the long term efficacy of unilateral pallidotomy, a technique which has gained popularity over the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8334de1e486c89d2a3ec57438bb37372
https://doi.org/10.1136/jnnp.69.3.337

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Alzheimer's disease and parkinson's disease: Distinct entities or extremes of a spectrum of neurodegeneration?

Autor: D. B. Calne, C. W. Olanow, Daniel P. Perl

Publikováno v: Annals of Neurology. 44:S19-S31

Alzheimer's disease (AD) and Parkinson's disease (PD) are generally considered to be separate and distinct disease entities. However, a considerable amount of evidence demonstrates that these disorders share common clinical and neuropathologic featur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a78f0521340c3d2715affff333bec9ff
https://doi.org/10.1002/ana.410440705

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Striatal D2 receptors in symptomatic and asymptomatic carriers of dopa-responsive dystonia measured with [11C]-raclopride and positron-emission tomography

Autor: Edwin Mak, R. de la Fuente-Fernandez, Barry J. Snow, Thomas J. Ruth, T. G. Nygaard, A. J. Stoessl, D. B. Calne, A. B. Naini, Michael Schulzer, Asha Kishore

Publikováno v: Neurology. 50:1028-1032

We tested the hypothesis that asymptomatic carriers of dopa-responsive dystonia (DRD) have increased dopamine D2 receptors in the striatum that protect them from the clinical manifestations of dopaminergic deficiency. We examined striatal D2-receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d2c8329986315711c1e1ce806036673
https://doi.org/10.1212/wnl.50.4.1028

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Efficacy, stability and predictors of outcome of pallidotomy for Parkinson's disease. Six-month follow-up with additional 1-year observations

Autor: I M Turnbull, S Yardley, Asha Kishore, R. de la Fuente-Fernandez, Edwin Mak, Michael Schulzer, D. B. Calne, Barry J. Snow

Publikováno v: Brain. 120:729-737

We tested the efficacy, stability and predictors of outcome of unilateral pallidotomy used to treat patients with Parkinson's disease inadequately controlled with pharmacotherapy (IP). The surgical procedure was as simple as possible; we used CT rath

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd134ff3cebf365c82fce32d90130d4
https://doi.org/10.1093/brain/120.5.729

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