Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D B, McClure"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 12, Pp 2586-2598 (1996)
LY295427, (3 alpha,4 alpha,5 alpha)-4-(2-propenylcholestan-3-ol), acts through an unknown mechanism to derepress the transcription of the low density lipoprotein (LDL) receptor in the presence of 25-hydroxycholesterol (25-OH chol). Preincubation with
Externí odkaz:
https://doaj.org/article/7a420e292d0b4a7ca882eb07482c5155
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 5, Pp 1162-1166 (1996)
Cholesteryl ester transfer protein (CETP) mediates the exchange of phospholipids and neutral lipids between the plasma lipoproteins, and plays an important role in high density lipoprotein (HDL) metabolism. While there are reports of low-level CETP s
Autor:
M W Warrick, David T. Berg, Philip J. Burck, D B McClure, B Weigel, S R Jaskunas, David H. Berg, Chris J. Vlahos, J D Walls, R M Crisel
Publikováno v:
Journal of Biological Chemistry. 265:5170-5177
To study structure/function relationships of tissue plasminogen activator (t-PA) activity, one of the simplest modified t-PA structures to activate plasminogen in a fibrin-dependent manner was obtained by constructing an expression vector that delete
Autor:
H S, Lin, A A, Rampersaud, M E, Richett, R W, Harper, L S, Beavers, D B, McClure, A J, Gardner, P I, Eacho, P S, Foxworthy, R A, Gadski
Publikováno v:
Steroids. 64(3)
4Alpha-(2-propenyl)-5alpha-cholestan-3alpha-ol (LY295427) was previously identified from a Chinese hamster ovary (CHO) cell-based low density lipoprotein receptor/luciferase (LDLR/Luc) assay to be a potent transcriptional activator of the LDL recepto
Autor:
W R, Bensch, R A, Gadski, J S, Bean, L S, Beavers, R J, Schmidt, D N, Perry, A T, Murphy, D B, McClure, P I, Eacho, A P, Breau, R A, Archer, R F, Kauffman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 289(1)
The action of LY295427 [(3alpha,4alpha, 5alpha)-4-(2-propenylcholestan-3-ol)], a compound that derepresses low-density lipoprotein receptor (LDL-R) expression in a cell-based model, was examined in hamsters. It was found that the compound does not ha
Publikováno v:
Steroids. 63(4)
4 alpha-(2-Propenyl)-5 alpha-cholestan-3 alpha-ol (LY295427) was previously identified from a CHO cell-based assay to be a potent LDL receptor up-regulator and had demonstrated to be an effective agent in lowering plasma cholesterol levels in hyperch
Publikováno v:
BioTechniques. 14(6)
We have developed a host cell/vector system based on the use of adenovirus-transformed cells and a promoter, designated GBMT, capable of being activated by the Ela tumor antigen produced in these cells. GBMT-based vectors were constructed with hygrom
Autor:
P J, Burck, D H, Berg, M W, Warrick, D T, Berg, J D, Walls, S R, Jaskunas, R M, Crisel, B, Weigel, C J, Vlahos, D B, McClure
Publikováno v:
The Journal of biological chemistry. 265(9)
To study structure/function relationships of tissue plasminogen activator (t-PA) activity, one of the simplest modified t-PA structures to activate plasminogen in a fibrin-dependent manner was obtained by constructing an expression vector that delete
Publikováno v:
The Journal of Cell Biology
In this communication we describe serum-free culture conditions for the serial propagation of the C6 glioma cell line. The growth rate, saturation density, and morphology of these cells are equivalent to those of their serum-grown counterparts when c
Autor:
D B, McClure
Publikováno v:
The Journal of the American College of Dentists. 43(2)