Výsledky vyhledávání - "D B, Hoelzinger"

Glioma cell motility is associated with reduced transcription of proapoptotic and proliferation genes: a cDNA microarray analysis

Autor: L, Mariani, C, Beaudry, W S, McDonough, D B, Hoelzinger, T, Demuth, K R, Ross, T, Berens, S W, Coons, G, Watts, J M, Trent, J S, Wei, A, Giese, M E, Berens

Publikováno v: Journal of neuro-oncology. 53(2)

Microarray analysis of complementary DNA (cDNA) allows large-scale, comparative, gene expression profiling of two different cell populations. This approach has the potential for elucidating the primary transcription events and genetic cascades respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d9ef321c2049834897635c0ba98b468
https://pubmed.ncbi.nlm.nih.gov/11716068

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Death-associated protein 3 (Dap-3) is overexpressed in invasive glioblastoma cells in vivo and in glioma cell lines with induced motility phenotype in vitro

Autor: L, Mariani, C, Beaudry, W S, McDonough, D B, Hoelzinger, E, Kaczmarek, F, Ponce, S W, Coons, A, Giese, R W, Seiler, M E, Berens

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 7(8)

To discover the genetic determinants of glioma invasion in vivo, we compared the mRNA expression profiles of glioblastoma cells residing at the tumor core versus those at the invasive rim of a human tumor resection.From a single glioblastoma specimen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4e939a24c8a3669bad7ba987af32844a
https://pubmed.ncbi.nlm.nih.gov/11489830

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Identification and validation of P311 as a glioblastoma invasion gene using laser capture microdissection

Autor: L, Mariani, W S, McDonough, D B, Hoelzinger, C, Beaudry, E, Kaczmarek, S W, Coons, A, Giese, M, Moghaddam, R W, Seiler, M E, Berens

Publikováno v: Cancer research. 61(10)

The mRNA expression profiles from glioblastoma cells residing at the tumor core and invasive rim of a human tumor resection were compared. From a single tumor specimen, 20,000 single cells from each region were collected by laser capture microdissect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::95a328511defdb5a6921b8896671cf6d
https://pubmed.ncbi.nlm.nih.gov/11358844

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Identification of transforming growth factor-beta1-binding protein overexpression in carmustine-resistant glioma cells by MRNA differential display

Autor: S A, Norman, S N, Rhodes, S, Treasurywala, D B, Hoelzinger, J, Rankin Shapiro, A C, Scheck

Publikováno v: Cancer. 89(4)

The authors previously demonstrated the presence of cells in primary human malignant gliomas that intrinsically are resistant to carmustine (BCNU). Numerous studies have identified mechanisms of therapy resistance in these cells; however, the authors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7ae260d7ff89a4476f71d78f9ad08d3
https://pubmed.ncbi.nlm.nih.gov/10951349

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