Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D B, Brunner"'
Autor:
D B, Brunner, G, Desponds, J, Biollaz, I, Keller, F, Ferber, H, Gavras, H R, Brunner, J L, Schelling
Publikováno v:
British journal of clinical pharmacology. 58(7)
Publikováno v:
Clinical chemistry. 47(4)
The renal enzyme renin cleaves from the hepatic alpha(2)-globulin angiotensinogen angiotensin-(1-10) decapeptide [Ang-(1-10)], which is further metabolized to smaller peptides that help maintain cardiovascular homeostasis. The Ang-(1-7) heptapeptide
Publikováno v:
Biorheology. 32:272-272
Autor:
William B. Abrams, Turini Ga, HJ Gomez, Hans R. Brunner, K. H. Jones, M Burnier, M. Porchet, D. B. Brunner, Jérôme Biollaz, Gavras H, F Ferber
Publikováno v:
Clinical Pharmacology and Therapeutics. 29:665-670
Three new angiotensin converting-enzyme inhibitors were given orally to 20 men in single doses ranging from 1.25 to 40 mg. Two of them induced comparable marked inhibition of both the blood pressure response to exogenous angiotensin I and plasma conv
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 244:H259-H265
A radioimmunoassay was set up to measure plasma arginine vasopressin levels (AVP). Characteristics of the assay include a sensitivity to 0.25 pg, high specificity of the antibody, mean recovery of added unlabeled arginine vasopressin of 80%, and an i
Autor:
Jérôme Biollaz, D. B. Brunner, G Desponds, H. R. Brunner, F Ferber, Schelling Jl, I. Keller, Haralambos Gavras
Publikováno v:
British Journal of Clinical Pharmacology. 11:461-467
1 MK 421 and its lysine analogue are two new inhibitors of angiotensin converting enzyme. Ten mg of both compounds were each given p.o. to 12 normotensive volunteers to determine their effect on the various components of the renin angiotensin aldoste
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 243:E450-E457
The role of angiotensin II in the stimulation of aldosterone biosynthesis by sodium sequestration in potassium-deficient rats was assessed by experiments involving 1-day angiotensin II infusion, converting enzyme inhibition, and bilateral nephrectomy
Autor:
B Jacot Des Combes, Schelling Jl, D. B. Brunner, HJ Gomez, M Hichens, EH Ulm, Jérôme Biollaz, G Desponds, H. R. Brunner
Publikováno v:
British Journal of Clinical Pharmacology. 14:363-368
1 Two single doses of 10 mg each of the converting enzyme inhibitor enalapril maleate or MK-421 and of its lysine analogue (MK-521) were administered p.o. to twelve male volunteers. 2 The active diacid metabolite of MK-421 and the lysine analogue wer
Publikováno v:
The American journal of physiology. 245(2)
The role of vasopressin, the renin system, and sympathetic activity in sustaining blood pressure in the dehydrated state was investigated in normotensive nonanesthetized male Wistar rats. After 48-h dehydration, plasma arginine vasopressin was 14.0 +
Publikováno v:
The Journal of laboratory and clinical medicine. 103(2)
Current radioimmunoassays do not demonstrate total absence of angiotensin II during converting enzyme inhibition. To assess the meaning of plasma angiotensin II determinations during converting enzyme inhibition, plasma angiotensin I and II levels of