Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D Abdirama"'
Autor:
Nina Babel, Gabriela Riemekasten, Falk Hiepe, Gerd-Rüdiger Burmester, Jens Y Humrich, Ulrik Stervbo, Christian Meisel, Sebastian Tesch, Petra Bacher, Andreas Radbruch, Anna-Sophie Grießbach, Alexander Scheffold, Tobias Alexander, Philipp Enghard, D Abdirama, Caroline von Spee-Mayer, Kai-Uwe Eckardt, Robert Biesen
Publikováno v:
Kidney International. 99:238-246
Systemic lupus erythematosus is a systemic and chronic autoimmune disease characterized by loss of tolerance towards nuclear antigens with autoreactive CD4+ T cells implicated in disease pathogenesis. However, very little is known about their recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc508c8094d1c936f8a978ba76b03c1c
https://doi.org/10.1016/j.kint.2020.05.051
https://doi.org/10.1016/j.kint.2020.05.051
Autor:
V. Langhans, S. Tesch, D. Abdirama, H. Brand, M. Bertolo, S. Baumgart, A. Paliege, G. Riemekasten, P. Enghard
Publikováno v:
Kidney International Reports, Vol 1, Iss 4, Pp S19-S20 (2016)
Externí odkaz:
https://doaj.org/article/6008b1db1613489087df94dec91da96d
Autor:
S. Tesch, A.S. Grieβbach, D. Abdirama, U. Stervbo, N. Babel, A. Radbruch, G. Riemekasten, P. Enghard
Publikováno v:
Kidney International Reports, Vol 1, Iss 4, Pp S21-S22 (2016)
Externí odkaz:
https://doaj.org/article/c52952efed9445dda256c42181d2b7ee
Autor:
Gerd-Rüdiger Burmester, Bruno Stuhlmüller, D Abdirama, Elise Siegert, Andreas Radbruch, Philipp Enghard, Eugen Feist, Tobias Alexander, Martina Bertolo, Dörte Huscher, Caroline von Spee-Mayer, A. Rose, Jens Y Humrich, Gabriela Riemekasten, Birgit Sawitzki, Falk Hiepe
Publikováno v:
The Lancet Rheumatology. 1:e44-e54
Summary Background An acquired deficiency of interleukin-2 (IL-2) and related defects in regulatory T cell homeostasis are thought to play a crucial role in the pathogenesis of systemic lupus erythematosus. We hypothesised that reconstitution of regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c40936f43ad0656320a09207a211c9ee
https://doi.org/10.1016/s2665-9913(19)30018-9
https://doi.org/10.1016/s2665-9913(19)30018-9
Publikováno v:
SATURDAY, 15 JUNE 2019.
Background Chronobiological aspects play an important role in rheumatoid arthritis (RA), with major symptoms such as joint pain and stiffness follow a day-night-cycle that peak in the early morning. The circadian behavior of symptoms has been attribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f1195a61102a2f3b25ebf31562bd46d
https://doi.org/10.1136/annrheumdis-2019-eular.1352
https://doi.org/10.1136/annrheumdis-2019-eular.1352
Autor:
Falk Hiepe, C. von Spee-Mayer, Bruno Stuhlmüller, G.-R. Burmester, Martina Bertolo, Philipp Enghard, Andreas Radbruch, D Abdirama, G. Riemekasten, Eugen Feist, Tobias Alexander, Jens Y Humrich, A. Rose, Elise Siegert
Publikováno v:
Abstracts.
Career situation of first and presenting author Instructor. Objectives An acquired deficiency of interleukin-2 (IL-2) and related defects in regulatory T cell (Treg) homeostasis play a crucial role in the pathogenesis of SLE. Here, we report the resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e141b83c2a4504dde8d88b80c5d2e6b
https://doi.org/10.1136/annrheumdis-2018-ewrr2019.121
https://doi.org/10.1136/annrheumdis-2018-ewrr2019.121
Publikováno v:
Rheumatoid arthritis – etiology, pathogenesis and animal models.
Background Clinical symptoms of rheumatoid arthritis (RA), such as join stiffness, swelling and pain, manifest in circadian pattern with the highest intensity occurs at early dawn. This is known to correlate with the circadian expression of IL-6, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a22209a2130bdf5dfae80d80ac873b0
https://doi.org/10.1136/annrheumdis-2018-eular.2525
https://doi.org/10.1136/annrheumdis-2018-eular.2525
Autor:
G.-R. Burmester, G. Riemekasten, Jens Y Humrich, S. Tesch, Ulrik Stervbo, Nina Babel, Philipp Enghard, Alexander Scheffold, A-S Griessbach, D Abdirama, Andreas Radbruch
Publikováno v:
Poster session 5: Innate and adaptive immunity.
Background and objectives Loss of tolerance towards nuclear antigens such as SmD1, RNP70, Histone, Ro, and La due to defective defective disposal of biological waste is characteristic of SLE. The question whether CD4 +T cells reactive to the aforemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5abe024812a7b6a7f1768022ef24d4bd
https://doi.org/10.1136/lupus-2018-abstract.146
https://doi.org/10.1136/lupus-2018-abstract.146
Autor:
Falk Hiepe, Gerd-Rüdiger Burmester, Tobias Alexander, Gabriela Riemekasten, Anika Klaus, D Abdirama, Elise Siegert, Caroline von Spee-Mayer, A. Rose, Jens Y Humrich, Andreas Radbruch, Birgit Sawitzki, Philipp Enghard
Publikováno v:
Annals of the Rheumatic Diseases. 75:1407-1415
Objectives Defects in regulatory T cell (Treg) biology have been associated with human systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). However, the origin of such Treg defects and their significance in the pathogenesis and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7764b6d44f81dcfb3569a161ad6b319
https://doi.org/10.1136/annrheumdis-2015-207776
https://doi.org/10.1136/annrheumdis-2015-207776
Autor:
Jens Y Humrich, Caroline von Spee-Mayer, A. Rose, Falk Hiepe, Gabriela Riemekasten, Gerd-Rüdiger Burmester, Elise Siegert, D Abdirama, Andreas Radbruch, Tobias Alexander, Philipp Enghard, Martina Bertolo
Publikováno v:
Novel technologies.
Background/purpose Interleukin-2 (IL-2) is crucial for the growth and survival of regulatory T cells (Treg), and thus for the control of autoimmunity. In previous studies we revealed the significance of an acquired IL-2 deficiency and related Treg de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c8c2f4aa5179dde77af05f7ae3cd0d
https://doi.org/10.1136/annrheumdis-2016-211053.8
https://doi.org/10.1136/annrheumdis-2016-211053.8