Výsledky vyhledávání - "D A Skerrett-Byrne"

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia

Autor: S Degryse, C E de Bock, S Demeyer, I Govaerts, S Bornschein, D Verbeke, K Jacobs, S Binos, D A Skerrett-Byrne, H C Murray, N M Verrills, P Van Vlierberghe, J Cools, M D Dun

Publikováno v: Leukemia
LEUKEMIA

Mutations in the interleukin-7 receptor (IL7R) or the JAK3 kinase occur frequently in T-cell acute lymphoblastic leukemia (T-ALL) and both are able to drive cellular transformation and the development of T-ALL in mouse models. However, the signal tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978628fca2940d7e5b024bd69665c145
http://europepmc.org/articles/PMC5843905

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