Zobrazeno 1 - 10
of 78
pro vyhledávání: '"D A Parish"'
Autor:
Atul Purohit, Christopher R. Ireson, Surinder K. Chander, Simon P. Newman, B V L Potter, D. C. Parish, S Perera, A C Smith, Michael J. Reed, M P Leese
Publikováno v:
British Journal of Cancer
2-Methoxyoestradiol (2-MeOE2) is an endogenous oestrogen metabolite that inhibits the proliferation of cancer cells in vitro, and it is also antiangiogenic. In vivo 2-MeOE2, when administered at relatively high doses, inhibits the growth of tumours d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53471e207db94c78cbeb0a9c261cb136
https://doi.org/10.1038/sj.bjc.6601591
https://doi.org/10.1038/sj.bjc.6601591
Autor:
Lawrence W. L. Woo, D. C. Parish, Christopher R. Ireson, Surinder K. Chander, Michael J. Reed, Atul Purohit, Barry V. L. Potter
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 84:337-342
Steroid sulphatase inhibitors which decrease or prevent the biosynthesis of oestrogens, potentially have an important role in the treatment of breast cancer in postmenopausal women. The non-steroidal sulphatase inhibitor 667 COUMATE has been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90595fad6b6356ef6bc0c1e08d05ec7e
https://doi.org/10.1016/s0960-0760(03)00047-5
https://doi.org/10.1016/s0960-0760(03)00047-5
Autor:
Michele Vadursi, Konstantinos G. Kyriakopoulos, D. J. Parish, Leopoldo Angrisani, Aniello Napolitano, William Whittow
Publikováno v:
2010 IEEE Instrumentation & Measurement Technology Conference Proceedings.
Wireless networks such as WiFi suffer communication performance issues in addition to those seen on wired networks due to the characteristics of the radio communication channel used by their Physical Layers (PHY). Understanding these issues is a comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe0999900375ddc0cd1abde7718bc5e
https://doi.org/10.1109/imtc.2010.5488062
https://doi.org/10.1109/imtc.2010.5488062
Publikováno v:
Cytogenetic and Genome Research. 96:191-197
The Lyon repeat hypothesis postulates that long interspersed elements (LINEs) play a role in X-chromosome inactivation. Evidence to support this hypothesis includes the observation that the degree of inactivation of autosomes translocated to the X ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e70268fa3542568e2bf5710e96b8b4b4
https://doi.org/10.1159/000063038
https://doi.org/10.1159/000063038
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 79:165-172
The cytokine interleukin-6 (IL-6) and its soluble receptor (IL-6sR) can act synergistically to stimulate aromatase activity in cultured stromal fibroblasts derived from breast tissues. In this study, a 16 amino acid peptide, AROHIB, has been used in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f763a6ca8e0f84c605b86b58105d370
https://doi.org/10.1016/s0960-0760(01)00155-8
https://doi.org/10.1016/s0960-0760(01)00155-8
Autor:
D C Parish
Publikováno v:
Endocrine Related Cancer. 5:223-229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97422404a486a3d974c9c205354cc2b9
https://doi.org/10.1677/erc.0.0050223
https://doi.org/10.1677/erc.0.0050223
1553 emulation over ATM (asynchronous transfer mode) - A hybrid avionics communications architecture
Publikováno v:
IEEE Aerospace and Electronic Systems Magazine. 13:34-39
The issue of meeting the higher communications requirements of future aircraft avionics systems in an incremental manner is addressed. A communications architecture is proposed which is based upon a switched network technology from the telecommunicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e469efcd2c085192f413401cfe1d3533
https://doi.org/10.1109/62.659862
https://doi.org/10.1109/62.659862
Autor:
Atul Purohit, Michael J. Reed, Barry V. L. Potter, Colin W. Pouton, Ulrike G. Sahm, M.I.Hidalgo Aragones, D. C. Parish
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 58:611-617
The sulphatase pathway is thought to be the major route of oestrogen synthesis in breast tumours in postmenopausal women. There is currently considerable interest in developing a potent steroid sulphatase inhibitor to block oestrogen synthesis by thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed54e740a19a548297d77faff51ed262
https://doi.org/10.1016/0960-0760(96)00074-x
https://doi.org/10.1016/0960-0760(96)00074-x
Autor:
J. Van Der Greef, F Smith, R.C. van der Schors, Connie R. Jimenez, Ka Wan Li, R. M. Hoek, S Chen, D C Parish, P R Benjamin, P. A. Van Veelen
Publikováno v:
Journal of Biological Chemistry. 269:30288-30292
A novel strategy combining peptide fingerprinting of single neurons by matrix-assisted laser desorption ionization mass spectrometry, molecular cloning, peptide chemistry, and electrospray ionization mass spectrometry was used to study the intricate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e78d66980047fadd5560cfc32184cb3b
https://doi.org/10.1016/s0021-9258(18)43810-0
https://doi.org/10.1016/s0021-9258(18)43810-0
Autor:
N Tezapsidis, D C Parish
Publikováno v:
Biochemical Journal. 301:607-614
A metalloprotease has been identified in ovine chromaffin granules which cleaves the proenkephalin fragment BAM12P to produce adrenorphin-Gly. This cleavage occurs at a single arginine residue and is an intermediate step in the production of the opia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9672c9ab369b93180c95432ab3de5657
https://doi.org/10.1042/bj3010607
https://doi.org/10.1042/bj3010607