Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D A Kirschmann"'
The association of HLA-DR alleles and T cell activation with allergic bronchopulmonary aspergillosis
Autor:
B Chauhan, L Santiago, D A Kirschmann, V Hauptfeld, A P Knutsen, P S Hutcheson, S L Woulfe, R G Slavin, H J Schwartz, C J Bellone
Publikováno v:
The Journal of Immunology. 159:4072-4076
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease caused by the mold Aspergillus fumigatus. We previously reported that the majority of T cell clones (TCC) isolated from three ABPA patients, and specific for a dominant
Publikováno v:
The Journal of Immunology. 155:5655-5662
Naturally processed peptides from immunoaffinity-purified HLA-DRB1*0401, -DRB1*0404 (rheumatoid arthritis (RA)-associated), and -DRB1*0402 (non-RA-associated) molecules were analyzed by capillary liquid chromatography and mass spectrometry. The molec
Metastasis to bone, liver and lungs is the primary cause of death in breast cancer patients. Our studies have revealed that the novel tumor suppressor Pdcd4 inhibits breast cancer cell migration and invasion in vitro. Loss of Pdcd4 in human nonmetast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfa07c0d5fd4d5dfccff3b0520c6264
https://europepmc.org/articles/PMC3419530/
https://europepmc.org/articles/PMC3419530/
Autor:
Z, Khalkhali-Ellis, E A, Seftor, D R, Nieva, R J, Handa, R H, Price, D A, Kirschmann, V M, Baragi, R V, Sharma, R C, Bhalla, T L, Moore, M J, Hendrix
Publikováno v:
The Journal of rheumatology. 27(7)
Despite increasing evidence regarding the significance of sex hormones in rheumatoid arthritis (RA), their etiopathological role and potential longterm effect on joint destruction remain unclear. We hypothesized that estrogen receptors (ER-alpha) are
Autor:
D A, Kirschmann, R A, Lininger, L M, Gardner, E A, Seftor, V A, Odero, A M, Ainsztein, W C, Earnshaw, L L, Wallrath, M J, Hendrix
Publikováno v:
Cancer research. 60(13)
We previously identified a down-regulation in heterochromatin-associated protein 1 (HP1)Hsalpha expression in MDA-MB-231 breast carcinoma cells (highly invasive/metastatic) compared with MCF-7 cells (poorly invasive/nonmetastatic). In this study, we
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 163(8)
Immune complexes that vary in size and composition are present in the sera and synovial fluid of juvenile rheumatoid arthritis (JRA) patients. They are believed to be potent inducers of the ongoing inflammatory process in JRA. However, the precise co
Autor:
N, Sharma, J, Luo, D A, Kirschmann, Y, O'Malley, M E, Robbins, E T, Akporiaye, D M, Lubaroff, P M, Heidger, M J, Hendrix
Publikováno v:
Cancer research. 59(10)
The Dunning R-3327 rat prostatic adenocarcinoma is a widely accepted model for in vivo experimental studies of prostate cancer. We have previously derived phenotypically distinct cell lines from a s.c. tumor resulting from the inoculation of the R-33
Autor:
S L, Woulfe, C P, Bono, M L, Zacheis, J K, Welply, D A, Kirschmann, T A, Baudino, Y, Wang, D A, Stone, G J, Hanson, J L, Vuletich, L J, Bedell, B D, Schwartz, S C, Howard
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(2)
The ability of a peptidomimetic (SC-67655) to block the peptide binding site of the rheumatoid arthritis-linked human leukocyte antigen encoded by the DRB1*0401 allele was evaluated. The inhibitor bound to purified DRB1*0401 molecules with an affinit
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