Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D A Kaehler"'
Publikováno v:
Journal of Immunological Methods. 197:85-95
ABL-MYC is a recombinant retrovirus that constitutively expresses the v-abl and c-myc oncogenes. When used to infect immunized mice this virus rapidly and efficiently induces plasmacytomas of which an unusually high percentage secrete antigen (Ag)-sp
Publikováno v:
Proceedings of the National Academy of Sciences. 88:3700-3704
Molecular analysis has shown that the majority of Abelson murine leukemia virus (Ab-MuLV)-induced primary thymomas represent transformed gamma/delta thymocytes. Many of these thymomas are of monoclonal origin as judged by provirus integration pattern
Autor:
J F Mushinski, Sandra J. Smith-Gill, Harald Mischak, T Mitchell, R Risser, D A Kaehler, Eva M. Weissinger, David A Largaespada
Publikováno v:
Scopus-Elsevier
ABL-MYC, a recombinant murine retrovirus that expresses v-abl and c-myc, rapidly induces transplantable mono- or oligoclonal plasmacytomas in BALB/c mice. To determine if the targets for transformation of this retrovirus are antigen-committed B lymph
Publikováno v:
Journal of virology. 64(5)
The Drosophila melanogaster abl and the murine v-abl genes encode tyrosine protein kinases (TPKs) whose amino acid sequences are highly conserved. To assess functional conservation between the two gene products, we constructed Drosophila abl/v-abl-ch
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642758911
Evidence from many laboratories indicates that v-abl and c-myc oncogenes both can participate in the induction of B-cell neoplasia, and under appropriate conditions both may synergize in that process. The first indication of the interaction of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d38770bc48093a71437b987ec48dfef
https://doi.org/10.1007/978-3-642-75889-8_13
https://doi.org/10.1007/978-3-642-75889-8_13
Publikováno v:
Journal of Virology. 55:547-553
The susceptibility of mice to lymphoma induction by Moloney or Abelson murine leukemia virus has been compared in BALB/c, C57BL/6, and BALB/cXC57BL/6 recombinant inbred strains. BALB/c mice were found to be susceptible to lymphoma induction by either
Publikováno v:
Journal of Virology. 61:2192-2197
We examined the clonality of tumors induced by an acutely transforming retrovirus which carries a single oncogene. Contrary to our expectation, tumors induced by the Abelson murine leukemia virus (A-MuLV) showed one to four major proviral integration
Publikováno v:
Proceedings of the National Academy of Sciences. 84:5932-5936
We investigated the role of the Moloney helper virus, Moloney murine leukemia virus (Mo-MuLV), in cell transformation and tumor induction by the defective Abelson murine leukemia virus (Ab-MuLV). A molecular clone of Ab-MuLV (P160 strain) was transfe
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783642740084
The Abelson murine leukemia virus (A-MuLV) rapidly induces pre-B cell lymphomas in susceptible mice (Risser et al., 1978) and transforms bone marrow lymphocytes in vitro (Rosenberg and Baltimore, 1976) when inoculated as a complex of virions containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6cc48faa83e45b7cfdb10ebab7eb167
https://doi.org/10.1007/978-3-642-74006-0_8
https://doi.org/10.1007/978-3-642-74006-0_8
Publikováno v:
Oncogene. 2(6)
The long terminal repeat (LTR) of the pre-B cell tropic Abelson murine leukemia virus (A-MuLV) was replaced with the LTR of the erythrotropic Friend MuLV or with the LTR of the erythropic/fibrotropic Harvey murine sarcoma virus (Ha-MuSV) to generate