Zobrazeno 1 - 10 of 36 pro vyhledávání: '"D A Cantrell"'
1
An analysis of the role of guanine nucleotide binding proteins in antigen receptor/CD3 antigen coupling to phospholipase C
Autor: J D Graves, D A Cantrell
Publikováno v: The Journal of Immunology. 146:2102-2107
In permeabilized human T lymphocytes, phospholipase C (PLC)-mediated metabolism of polyphosphatidylinositols can be stimulated by triggering the T cell antigen receptor/CD3 antigen complex (Ti/CD3) with the CD3 antibody UCHT1 or by activation of G pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::584c0db89afd23c10fb52f04baae3d3b
https://doi.org/10.4049/jimmunol.146.7.2102
Zobrazit plný text záznamu
2
Heterogeneity of the regulation of phospholipase C by phorbol esters in T lymphocytes
Autor: S G Ward, D A Cantrell
Publikováno v: The Journal of Immunology. 144:3523-3528
In many cells, protein kinase C (PKC) activation inhibits cellular phospholipase C thereby preventing receptor-mediated phosphatidylinositol (PI) metabolism. In T lymphocytes, the T cell antigen receptor (Ti)/CD3 complex regulates PI hydrolysis and w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8a37315032be3a6ddb74b0e43364c98
https://doi.org/10.4049/jimmunol.144.9.3523
Zobrazit plný text záznamu
3
Activation of human T lymphocytes via the CD2 antigen results in tyrosine phosphorylation of T cell antigen receptor zeta-chains
Autor: E Monostori, D Desai, M H Brown, D A Cantrell, M J Crumpton
Publikováno v: The Journal of Immunology. 144:1010-1014
The phosphorylation of the invariant chains associated with the human TCR has been investigated after the stimulation of T lymphocytes with CD2 mAb T11(2) and T11(3), PHA, or phorbol 12,13-dibutyrate. As described previously, stimulation of T cells w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2690f82f39b70371008231097b701bcc
https://doi.org/10.4049/jimmunol.144.3.1010
Zobrazit plný text záznamu
4
Control of pre-T cell proliferation and differentiation by the GTPase Rac-I
Autor: M, Gomez, V, Tybulewicz, D A, Cantrell
Publikováno v: Nature immunology. 1(4)
The GTPase Rac-I has the potential for pleiotropic functions due to its ability to interact with multiple effectors. Here, activation of Rac-I is shown to potently regulate pre-T cell differentiation and proliferation at the point of T cell antigen r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ecc5b05ab6aab73524304b919c2540f7
https://pubmed.ncbi.nlm.nih.gov/11017108
Zobrazit plný text záznamu
5
IL-12 selectively regulates STAT4 via phosphatidylinositol 3-kinase and Ras-independent signal transduction pathways
Autor: V, Athié-M, H, Flotow, K L, Hilyard, D A, Cantrell
Publikováno v: European journal of immunology. 30(5)
IL-12 is an important immunomodulatory cytokine that induces tyrosine phosphorylation and activation of the signal transducer and activator of transcription (STAT)4. IL-12 induces sustained activation and nuclear translocation of STAT4 and this regul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c51fd4340177ea25c8296f8fb9cca8d9
https://pubmed.ncbi.nlm.nih.gov/10820390
Zobrazit plný text záznamu
7
Interleukin-2 activation of STAT5 requires the convergent action of tyrosine kinases and a serine/threonine kinase pathway distinct from the Raf1/ERK2 MAP kinase pathway
Autor: C, Beadling, J, Ng, J W, Babbage, D A, Cantrell
Publikováno v: The EMBO journal. 15(8)
Interleukin-2 (IL-2) induces DNA binding of STAT5, a member of the family of cytokine-regulated transcription factors termed 'signal transducers and activators of transcription'. IL-2-stimulated STAT5-DNA complexes include two tyrosine phosphoprotein
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a0216fd67bff98986fe6fa295d465c0
https://pubmed.ncbi.nlm.nih.gov/8617237
Zobrazit plný text záznamu
8
Signal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor molecules
Autor: J A, Nunès, A, Truneh, D, Olive, D A, Cantrell
Publikováno v: The Journal of biological chemistry. 271(3)
This study compares the biochemical responses in T cells activated with the CD28 ligands B7-1 and B7-2. The patterns of tyrosine phosphorylation induced in T cells by these two CD28 ligands are identical, but clearly different from the tyrosine phosp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3f16240cef0db8183cfc12ee01d27172
https://pubmed.ncbi.nlm.nih.gov/8576157
Zobrazit plný text záznamu
9
Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation
Autor: E M, Genot, P J, Parker, D A, Cantrell
Publikováno v: The Journal of biological chemistry. 270(17)
T cells express multiple isotypes of protein kinase C (PKC) and although it is well accepted that PKCs have an important role in T cell activation, little is known about the function of individual PKC isotypes. To address this issue, mutationally act
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::995654ed69f8ac380c1157cf9227dbf7
https://pubmed.ncbi.nlm.nih.gov/7730364
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje