Výsledky vyhledávání - "D A Bernlohr"

Adenovirus-mediated gene transfer in primary murine adipocytes

Autor: A V, Hertzel, M A, Sanders, D A, Bernlohr

Publikováno v: Journal of lipid research. 41(7)

The transfer of genes into primary murine adipocytes using an adenovirus system has been developed. A recombinant adenovirus was constructed (expressing green fluorescent protein [GFP] under the control of the strong cytomegalovirus [CMV] promoter an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::faf23431ff44324742dc033fe577ce58
https://pubmed.ncbi.nlm.nih.gov/10884289

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Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels

Autor: N R, Coe, M A, Simpson, D A, Bernlohr

Publikováno v: Journal of lipid research. 40(5)

The availability of mice containing an adipocyte lipid-binding protein (ALBP/aP2) gene disruption allowed for a direct examination of the presumed role of lipid-binding proteins in the mobilization and trafficking of intracellular fatty acids. Total

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e6548e93009db525672581301e8016ab
https://pubmed.ncbi.nlm.nih.gov/10224167

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Surface properties of adipocyte lipid-binding protein: Response to lipid binding, and comparison with homologous proteins

Autor: V J, LiCata, D A, Bernlohr

Publikováno v: Proteins. 33(4)

Adipocyte lipid-binding protein (ALBP) is one of a family of intracellular lipid-binding proteins (iLBPs) that bind fatty acids, retinoids, and other hydrophobic ligands. The different members of this family exhibit a highly conserved three-dimension

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::01f7adf923700188282de7bfe92f8e13
https://pubmed.ncbi.nlm.nih.gov/9849941

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Regulation of adipocyte gene expression by polyunsaturated fatty acids

Autor: A V, Hertzel, D A, Bernlohr

Publikováno v: Molecular and cellular biochemistry. 188(1-2)

A wide number of adipocyte genes are regulated by exogenous polyunsaturated fatty acids (PUFA) through the actions of the peroxisome proliferator activated receptor. Such genes include the adipocyte lipid-binding protein (ALBP or aP2) which plays a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a40dac1ac6bce4e8a344bcfa850aa124
https://pubmed.ncbi.nlm.nih.gov/9823008

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Fatty acid uptake in diabetic rat adipocytes

Autor: H, Fraser, S M, Coles, J K, Woodford, A A, Frolov, E J, Murphy, F, Schroeder, D A, Bernlohr, V, Grund

Publikováno v: Molecular and cellular biochemistry. 167(1-2)

The effect of diabetic status and insulin on adipocyte plasma membrane properties and fatty acid uptake was examined. Studies with inhibitors and isolated adipocyte ghost plasma membranes indicated 9Z, 11E, 13E, 15Z-octatetraenoic acid (cis-parinaric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dd1e1c0d5ebd323a8a86fce861cb79c5
https://pubmed.ncbi.nlm.nih.gov/9059981

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Regulation of gene expression in adipose cells by polyunsaturated fatty acids

Autor: D A, Bernlohr, N R, Coe, M A, Simpson, A V, Hertzel

Publikováno v: Advances in experimental medicine and biology. 422

In fat cells polyunsaturated fatty acids are both substrates for, and products of, triacylglycerol metabolism. Dietary fatty acids are efficiently incorporated into the triacylglycerol droplet under lipogenic conditions while rapidly mobilizing them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f725ba1c8a7dbbb8a48dda25072024f6
https://pubmed.ncbi.nlm.nih.gov/9361822

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Identification of a class of Saccharomyces cerevisiae mutants defective in fatty acid repression of gene transcription and analysis of the frm2 gene

Autor: M W, McHale, K D, Kroening, D A, Bernlohr

Publikováno v: Yeast (Chichester, England). 12(4)

Exogenous fatty acids transcriptionally control the expression of a wide variety of eukaryotic genes, many of which encode proteins involved in lipid metabolism. To identify gene products involved in the lipid signalling pathway, a reporter plasmid c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b54826e92d0f2923a182188f4dd6f7d7
https://pubmed.ncbi.nlm.nih.gov/8701605

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The up-and-down beta-barrel proteins

Autor: J M, LaLonde, D A, Bernlohr, L J, Banaszak

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 8(15)

The up-and-down beta-barrel is a common folding motif found frequently in proteins that bind and transport hydrophobic ligands. It is formed by an array of beta-strands arranged in an antiparallel manner with each strand hydrogen-bonded to neighborin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::466ac652c9dce69618d1c27e44bbaeb0
https://pubmed.ncbi.nlm.nih.gov/7737467

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Adipocyte lipid-binding protein complexed with arachidonic acid. Titration calorimetry and X-ray crystallographic studies

Autor: J M, LaLonde, M A, Levenson, J J, Roe, D A, Bernlohr, L J, Banaszak

Publikováno v: The Journal of biological chemistry. 269(41)

The association of the adipocyte lipid-binding protein (ALBP) with arachidonic acid (all cis, 20:4 delta 5,8,11,14) and oleic acid (cis, 18:1 delta 9) has been examined by titration calorimentry. In addition, the crystal structure of ALBP with bound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fb14ec0991d18ddca915be81989e2ad
https://pubmed.ncbi.nlm.nih.gov/7929228

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