Zobrazeno 1 - 10 of 33 pro vyhledávání: '"D A, Wink"'
1
Production of reactive oxygen species after reperfusion in vitro and in vivo: protective effect of nitric oxide
Autor: Ryszard M. Pluta, Edward H. Oldfield, Robert J. Boock, Stuart Walbridge, R B Mason, D A Wink
Publikováno v: Journal of Neurosurgery. 93:99-107
Object. Thrombolytic treatments for ischemic stroke can restore circulation, but reperfusion injury, mediated by oxygen free radicals, can limit their utility. The authors hypothesized that, during reperfusion, nitric oxide (NO) provides cytoprotecti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2245633f382b9bd988bb7568fccf6745
https://doi.org/10.3171/jns.2000.93.1.0099
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2
Exogenous nitric oxide regulates IFN-gamma plus lipopolysaccharide-induced nitric oxide synthase expression in mouse macrophages
Autor: L A Sheffler, D A Wink, G Melillo, G W Cox
Publikováno v: The Journal of Immunology. 155:886-894
This study was performed to determine the effects of nitric oxide (NO) on the expression of inducible NO synthase (iNOS) in mouse macrophages. We used the NO donor diethylamine dinitric oxide (DEA/NO) and the mouse macrophage cell line ANA-1 in these
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4af9efbabcbce2bd920550cfcb8a946
https://doi.org/10.4049/jimmunol.155.2.886
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3
Reaction Kinetics for Nitrosation of Cysteine and Glutathione in Aerobic Nitric Oxide Solutions at Neutral pH. Insights into the Fate and Physiological Effects of Intermediates Generated in the NO/O2 Reaction
Autor: D A, Wink, R W, Nims, J F, Darbyshire, D, Christodoulou, I, Hanbauer, G W, Cox, F, Laval, J, Laval, J A, Cook, M C, Krishna
Publikováno v: Chemical Research in Toxicology. 7:519-525
The critical regulatory function of nitric oxide (NO) in many physiologic processes is well established. However, in an aerobic aqueous environment NO is known to generate one or more reactive and potentially toxic nitrogen oxide (NOx) metabolites. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3e8aa862a67ce37456436a1fc1cf56
https://doi.org/10.1021/tx00040a007
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6
Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid
Autor: J S, Isenberg, Y, Jia, L, Field, L A, Ridnour, A, Sparatore, P, Del Soldato, A L, Sowers, G C, Yeh, T W, Moody, D A, Wink, R, Ramchandran, D D, Roberts
Publikováno v: British journal of pharmacology. 151(1)
Angiogenesis involves multiple signaling pathways that must be considered when developing agents to modulate pathological angiogenesis. Because both cyclooxygenase inhibitors and dithioles have demonstrated anti-angiogenic properties, we investigated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8ae843bf112967e894b270bfb2efa9c
https://pubmed.ncbi.nlm.nih.gov/17351657
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7
Nitroxyl anion regulation of the NMDA receptor
Autor: C A, Colton, M, Gbadegesin, D A, Wink, K M, Miranda, M G, Espey, S, Vicini
Publikováno v: Journal of neurochemistry. 78(5)
Nitric oxide (NO) is an important regulator of NMDA channel function in the CNS. Recent findings suggest that nitroxyl anion (NO(-)) may also be generated by nitric oxide synthase, which catalyzes production of NO. Using recombinant NMDA receptors (N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ebd5083f49e9528124a5b37d504a2593
https://pubmed.ncbi.nlm.nih.gov/11553686
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9
Effect of nitric oxide and nitric oxide donors on red blood cell oxygen transport
Autor: B W, Hrinczenko, A I, Alayash, D A, Wink, M T, Gladwin, G P, Rodgers, A N, Schechter
Publikováno v: British journal of haematology. 110(2)
A mechanism has been proposed in which nitric oxide (NO) may bind to cysteine beta93 and be transported by haemoglobin from the lungs to the tissues and modify vascular tone. In addition, it has been reported that treatment of sickle cell anaemia blo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a0a2742b03f4758df7cfa5e797a32b0
https://pubmed.ncbi.nlm.nih.gov/10971400
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10
Review article: chronic inflammation and reactive oxygen and nitrogen metabolism--implications in DNA damage and mutagenesis
Autor: M B, Grisham, D, Jourd'heuil, D A, Wink
Publikováno v: Alimentary pharmacologytherapeutics. 14
It is well known that chronic inflammation of the digestive tract is associated with an increased risk of malignant transformation. Because phagocytic leukocytes and cytokine-activated parenchymal cells produce large amounts of reactive metabolites o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::866416ff576eb1196d1eb823b37974d8
https://pubmed.ncbi.nlm.nih.gov/10807397
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