Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D A, Siebecker"'
Autor:
D J, Hnatowich, M, Rusckowski, D A, Siebecker, M, Gionet, G, Mardirossian, H S, Bushe, S, Roy, J A, Mattis, D, Shealy, T W, Griffin
Publikováno v:
Journal of nuclear biology and medicine (Turin, Italy : 1991). 36(1)
In a program to investigate patient pharmacokinetics of labeled anti-tumor antibodies, a study of the 10-3D2 anti-breast tumor antibody was conducted. The F(ab')2 fragment, coupled with DTPA, was radiolabeled with indium-111 and 1 mg (37 MBq, or 1 mC
Autor:
D J, Hnatowich, M, Rusckowski, A B, Brill, D A, Siebecker, H, Misra, G, Mardirossian, H, Bushe, A, Rescigno, S, Stevens, D K, Johnson
Publikováno v:
Cancer research. 50(22)
The pharmacokinetics of the C110 anti-carcinoembryonic antigen antibody radiolabeled with 111In via a novel benzylisothiocyanate derivative of diethylenetriamine pentaacetic acid have been determined in 12 patients. The chelator was attached to the p
Autor:
H P, Kalofonos, M, Rusckowski, D A, Siebecker, G B, Sivolapenko, D, Snook, J P, Lavender, A A, Epenetos, D J, Hnatowich
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 31(11)
Tumor localization in patients has been achieved through the in vivo use of streptavidin and biotin. In these preliminary studies, the monoclonal antibody HMFG1 was conjugated with streptavidin and 1 mg was administered intravenously to each of 10 pa
Pharmacokinetics of 111In-labeled OC-125 antibody in cancer patients compared with the 19-9 antibody
Autor:
D J, Hnatowich, M, Gionet, M, Rusckowski, D A, Siebecker, J, Roche, D, Shealy, J A, Mattis, J, Wilson, J, McGann, R E, Hunter
Publikováno v:
Cancer research. 47(22)
We recently reported on the pharmacokinetics in 14 cancer patients of the 19-9 antibody radiolabeled with 111In. We have now repeated this investigation in 18 cancer patients using the OC-125 antibody, in part to compare the in vivo behavior of two m
Autor:
D J, Hnatowich, M, Chinol, D A, Siebecker, M, Gionet, T, Griffin, P W, Doherty, R, Hunter, K R, Kase
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 29(8)
Although 90Y is one of the best radionuclides for radioimmunotherapeutic applications, the lack of gamma rays in its decay complicates the estimation of radiation dose since its biodistribution cannot be accurately determined by external imaging. A l