Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D A, Scudiero"'
Publikováno v:
ChemInform. 22
Publikováno v:
Journal of Medicinal Chemistry. 33:2579-2583
Aliphatic triazenes, such as 1,3-dimethyltriazene, are potent biological alkylating agents because they form alkyldiazonium ions. They are also subject to very rapid proteolytic decomposition, even at physiological pH. The acylated analogues 1,3-dial
Autor:
I, Tamm, S M, Kornblau, H, Segall, S, Krajewski, K, Welsh, S, Kitada, D A, Scudiero, G, Tudor, Y H, Qui, A, Monks, M, Andreeff, J C, Reed
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
Expression of several inhibitor of apoptosis proteins (IAPs) was investigated in the National Cancer Institute panel of 60 human tumor cell lines, and the expression and prognostic significance of one of these, XIAP, was evaluated in 78 previously un
Publikováno v:
Cancer research. 58(23)
Survivin is a member of the inhibitor of apoptosis protein (IAP) family. We investigated the antiapoptotic mechanism of Survivin, as well as its expression in 60 human tumor cell lines used for the National Cancer Institute's anticancer drug screenin
Publikováno v:
Anti-cancer drug design. 12(7)
Autor:
L, Wu, A M, Smythe, S F, Stinson, L A, Mullendore, A, Monks, D A, Scudiero, K D, Paull, A D, Koutsoukos, L V, Rubinstein, M R, Boyd
Publikováno v:
Cancer research. 52(11)
Disease-oriented panels of human tumor cell lines used by the National Cancer Institute for large-scale in vitro anticancer drug screening were evaluated for multidrug-resistant phenotype at the functional (in vitro drug sensitivity) and molecular le
Autor:
D A Scudiero, Roger A. Brumback, J D Wirtschafter, Ronald J. Polinsky, Robert E. Tarone, Jay H. Robbins, R G Scarpinato, SusannaF. Barrett, Fujio Otsuka, Alan N. Moshell
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 47:391-398
Lymphoblastoid lines from nine Usher's syndrome (recessively inherited retinitis pigmentosa and congenital sensorineural deafness) patients (representing eight kindreds) and from ten Duchenne muscular dystrophy patients (representing seven kindreds)
Autor:
D A, Scudiero
Publikováno v:
Cancer research. 40(4)
DNA repair synthesis and posttreatment colony-forming ability were measured in six human fibroblast cell strains derived from patients with the autosomal recessive disorder, ataxia telangiectasia (AT), and five cell strains from normal individuals. A
Publikováno v:
Cancer research. 44(6)
In order to investigate the mechanisms of cellular damage by alkylating agents, human fibroblasts and tumor cell strains having different sensitivities to killing by N-methyl-N'-nitro-N-nitrosoguanidine [and different abilities to repair O6-methylgua
Autor:
R H, Shoemaker, A, Monks, M C, Alley, D A, Scudiero, D L, Fine, T L, McLemore, B J, Abbott, K D, Paull, J G, Mayo, M R, Boyd
Publikováno v:
Progress in clinical and biological research. 276