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Helicobacter pylori from asymptomatic hosts expressing heptoglycan but lacking Lewis O-chains: Lewis blood-group O-chains may play a role in Helicobacter pylori induced pathology

Autor: M A, Monteiro, F, St Michael, D A, Rasko, D E, Taylor, J W, Conlan, K H, Chan, S M, Logan, B J, Appelmelk, M B, Perry

Publikováno v: Biochemistry and cell biology = Biochimie et biologie cellulaire. 79(4)

Helicobacter pylori is a widespread Gram-negative bacterium responsible for the onset of various gastric pathologies and cancers in humans. A familiar trait of H. pylori is the production of cell-surface lipopolysaccharides (LPSs; O-chain --core --li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c7fb997799064296f63b525cfb96ee48
https://pubmed.ncbi.nlm.nih.gov/11527214

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Synthesis of mono- and di-fucosylated type I Lewis blood group antigens by Helicobacter pylori

Autor: D A, Rasko, G, Wang, M A, Monteiro, M M, Palcic, D E, Taylor

Publikováno v: European journal of biochemistry. 267(19)

The identification of Helicobacter pylori isolates that expresses exclusively type I Lewis antigens is necessary to determine the biosynthetic pathway of these antigens. Fast-atom bombardment MS provides evidence that the H. pylori isolate UA1111 exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ed04d76bb765e75b5cfda461b0c5cb66
https://pubmed.ncbi.nlm.nih.gov/10998067

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Lewis antigens in Helicobacter pylori: biosynthesis and phase variation

Autor: G, Wang, Z, Ge, D A, Rasko, D E, Taylor

Publikováno v: Molecular microbiology. 36(6)

The lipopolysaccharides (LPS) of most Helicobacter pylori strains contain complex carbohydrates known as Lewis antigens that are structurally related to the human blood group antigens. Investigations on the genetic determinants involved in the biosyn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fabd514342d7d367d7b903999221e168
https://pubmed.ncbi.nlm.nih.gov/10931272

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Lack of correlation between Lewis antigen expression by Helicobacter pylori and gastric epithelial cells in infected patients

Autor: D E, Taylor, D A, Rasko, R, Sherburne, C, Ho, L D, Jewell

Publikováno v: Gastroenterology. 115(5)

Lewis antigens are expressed by both human gastric epithelial tissue and Helicobacter pylori. We examined Lewis antigens expressed by gastric epithelium and by H. pylori isolated from the corresponding biopsy tissue.H. pylori Lewis expression was det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7161fa9e7ef1d781b444d0c9e8b077fe
https://pubmed.ncbi.nlm.nih.gov/9797366

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Simultaneous expression of type 1 and type 2 Lewis blood group antigens by Helicobacter pylori lipopolysaccharides. Molecular mimicry between h. pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms

Autor: M A, Monteiro, K H, Chan, D A, Rasko, D E, Taylor, P Y, Zheng, B J, Appelmelk, H P, Wirth, M, Yang, M J, Blaser, S O, Hynes, A P, Moran, M B, Perry

Publikováno v: The Journal of biological chemistry. 273(19)

Previous structural investigations performed on the lipopolysaccharides (LPSs) from the human gastric pathogen Helicobacter pylori have revealed that these cell surface glycan molecules express type 2 partially fucosylated, glucosylated, or galactosy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e772e07a99d9a87875b02a6e882d6d5d
https://pubmed.ncbi.nlm.nih.gov/9565568

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