Zobrazeno 1 - 7
of 7
pro vyhledávání: '"D A, Horita"'
Publikováno v:
Cell biochemistry and biophysics. 35(2)
SH3 domains are a conserved feature of many nonreceptor protein tyrosine kinases, such as Hck, and often function in substrate recruitment and regulation of kinase activity. SH3 domains modulate kinase activity by binding to polyproline helices (PPII
Publikováno v:
Journal of molecular biology. 310(1)
The complex and interrelated function of the interleukin cytokines relies on a range of pro-inflammatory and anti-inflammatory immune responses mediated by an array of receptors, and there is considerable cross-reactivity for related cytokines. Recen
Publikováno v:
Journal of molecular biology. 307(3)
The encapsulation of otherwise transcribable loci within transcriptionally inactive heterochromatin is rapidly gaining recognition as an important mechanism of epigenetic gene regulation. In the fission yeast Schizosaccharomyces pombe, heterochromati
Publikováno v:
Journal of biomolecular NMR. 19(1)
Publikováno v:
Journal of biomolecular NMR. 16(4)
Sorbitol is an excellent protein-stabilization agent, but it is typically used at high concentrations where the 1H signals can interfere with NMR data collection and analysis. Deuteration of sorbitol can ameliorate this problem; however, perdeuterate
Publikováno v:
Glycoconjugate journal. 14(5)
The anticoagulant properties of heparin are thought to derive from the inhibition of thrombin and other coagulation-related proteases by the binding of heparin to cofactors such as antithrombin III and heparin cofactor II. The apparent minimum native
Publikováno v:
The Journal of biological chemistry. 269(3)
Previous work has implicated sequences within the tandem repeats of cartilage link protein in the interaction of link protein with hyaluronan. This conclusion was based on competitive inhibition experiments using synthetic peptides (Goetinck, P. F.,