Výsledky vyhledávání - "D A, Gorelick"

Butyrylcholinesterase accelerates cocaine metabolism: in vitro and in vivo effects in nonhuman primates and humans

Autor: G N, Carmona, R A, Jufer, S R, Goldberg, D A, Gorelick, N H, Greig, Q S, Yu, E J, Cone, C W, Schindler

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 28(3)

Butyrylcholinesterase (BChE) is known to metabolize cocaine in humans. In the present study, three different experiments were performed to determine whether the addition of horse serum-derived BChE would accelerate the metabolism of cocaine. In the f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0745b496e005bf9f4e394d900dd16911
https://pubmed.ncbi.nlm.nih.gov/10681384

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Cigarette smoking during early cocaine abstinence

Autor: A, Radzius, D A, Gorelick, J E, Henningfield

Publikováno v: The American journal on addictions. 7(4)

Use of cocaine has been reported to increase cigarette smoking, but there are no published studies of cigarette smoking during early cocaine abstinence. The authors assessed ad libitum cigarette smoking of 12 cocaine-dependent smokers housed on a clo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a1e9aae14494a543e36e37b66ee47b7d
https://pubmed.ncbi.nlm.nih.gov/9809135

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Screening trauma patients for alcoholism according to NIAAA guidelines with alcohol use disorders identification test questions

Autor: C A, Soderstrom, P C, Dischinger, T J, Kerns, J A, Kufera, D R, McDuff, D A, Gorelick, G S, Smith

Publikováno v: Alcoholism, clinical and experimental research. 22(7)

Drinking pattern criteria (drinking frequency and number of drinks per occasion) issued by the National Institute on Alcohol and Abuse and Alcoholism (NIAAA) to screen primary practice patients for alcohol problems were evaluated in 1216 injured pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9a78eee777b9237e88331fe652315bf
https://pubmed.ncbi.nlm.nih.gov/9802530

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Mechanisms of alcohol craving and their clinical implications

Autor: E G, Singleton, D A, Gorelick

Publikováno v: Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism. 14

Craving for alcohol is frequently given as a reason for drinking and is often used as a surrogate measure in studies of alcoholism and its treatment. Despite this wide use, there is little consensus on what craving for alcohol means, the best way to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::42978d54bcd0996f36e43ecff2a671c2
https://pubmed.ncbi.nlm.nih.gov/9751946

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Attenuation of cocaine-induced locomotor activity by butyrylcholinesterase

Autor: G N, Carmona, C W, Schindler, M, Shoaib, R, Jufer, E J, Cone, S R, Goldberg, N H, Greig, Q S, Yu, D A, Gorelick

Publikováno v: Experimental and clinical psychopharmacology. 6(3)

A primary enzyme for the metabolism of cocaine is butyrylcholinesterase (BChE). To determine whether the systemic administration of BChE can increase the metabolism of cocaine sufficiently to alter a behavioral effect, rats were tested in a locomotor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48bc1c6b148c4a5e1fe3987e79acbc00
https://pubmed.ncbi.nlm.nih.gov/9725111

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The rate hypothesis and agonist substitution approaches to cocaine abuse treatment

Autor: D A, Gorelick

Publikováno v: Advances in pharmacology (San Diego, Calif.). 42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::427eb77d535012790c23eaff6c101405
https://pubmed.ncbi.nlm.nih.gov/9328065

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Characteristics of smoked drug use among cocaine smokers

Autor: D A, Gorelick, M S, Simmons, N, Carriero, D P, Tashkin

Publikováno v: The American journal on addictions. 6(3)

The authors collected data by structured interview from a convenience sample of 228 physically healthy, largely (82%) treatment-seeking, cocaine smokers with minimal histories of other smoked (other than tobacco and marijuana) or injection drug use.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7bdd1065aea1b7dd93378e3071dc8f2
https://pubmed.ncbi.nlm.nih.gov/9256990

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Psychoactive substance use disorders among seriously injured trauma center patients

Autor: C A, Soderstrom, G S, Smith, P C, Dischinger, D R, McDuff, J R, Hebel, D A, Gorelick, T J, Kerns, S M, Ho, K M, Read

Publikováno v: JAMA. 277(22)

To assess the prevalence of psychoactive substance use disorders (PSUDs) among a large, unselected group of seriously injured trauma center patients, using a standardized diagnostic interview and criteria.Prevalence study.A level I regional trauma ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::642e01c30e7a5be25fea0986457a4db5
https://pubmed.ncbi.nlm.nih.gov/9178789

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Changes in cigarette smoking not observed following repeated cocaine self-administration

Autor: A, Radzius, N J, Carriero, L L, Weinhold, D A, Gorelick, J E, Henningfield

Publikováno v: Experimental and clinical psychopharmacology. 5(1)

Acute administration of some psychoactive drugs (e.g., cocaine, heroin, methadone d-amphetamine) has been found to increase spontaneous cigarette smoking for 1-3 hr, but the effects of chronic drug administration have not been systematically studied.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::84cb713d548181961cfe73728d6e8385
https://pubmed.ncbi.nlm.nih.gov/9234039

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