Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D A, Eastmond"'
Publikováno v:
Environmental and molecular mutagenesis. 57(3)
o-Phenylphenol (OPP) is a widely used fungicide and antibacterial agent that at high doses has been shown to cause bladder cancer in male F344 rats. The mechanisms underlying OPP-induced bladder carcinogenicity remain unclear but it has been proposed
Publikováno v:
Environmental and molecular mutagenesis. 31(3)
Diethylstilbestrol (DES) and 17beta-estradiol (E2) are known inducers of aneuploidy and polyploidy in vivo and in vitro. Isolated human lymphocytes were treated with the stilbene estrogen DES (0.05-50 microM) and the steroid estrogen E2 (0.05-75 micr
Autor:
D S Rupa, D A Eastmond
Publikováno v:
Carcinogenesis. 18(12)
Epidemiological studies have shown that a high incidence of oral cancers is associated with chewing betel quid. Since chromosomal aberrations are involved in many types of cancers, we investigated whether increased frequencies of chromosomal alterati
Publikováno v:
Environmental and molecular mutagenesis. 29(2)
Chromosomal aberrations are associated with cancer, birth defects, and pregnancy loss. Previous studies using banding techniques have revealed that chromosomal alterations induced in human peripheral lymphocytes by many genotoxic agents occur nonrand
Publikováno v:
IARC scientific publications. (142)
Cytogenetic end-points have been successfully used in epidemiological studies for many years. Conventional end-points are now being replaced by procedures that utilize molecular methods, with greatly increased sensitivity, specificity and precision.
Publikováno v:
Cancer research. 55(3)
A novel multicolor fluorescence in situ hybridization approach, using an alpha satellite probe which labels the centromeric region on chromosome 1 and a classical satellite probe which targets an adjacent breakage-prone region (1q12), has been used t
Publikováno v:
Cancer research. 54(13)
Benzene is a widely recognized human and animal carcinogen. In spite of considerable research, relatively little is known about the genotoxic events that accompany benzene exposure in vivo. To gain insights into the mechanisms underlying the genotoxi
Publikováno v:
Chromosome Segregation and Aneuploidy ISBN: 9783642849404
Chromosomal abnormalities are believed to contribute significantly to human reproductive failure, carcinogenesis and other pathophysiological conditions (Hecht and Hecht, 1987; De Braekeleer and Dao, 1991). For example, approximately 15% of recognize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbca7c7f2e46a96b33ba91f27563d5c9
https://doi.org/10.1007/978-3-642-84938-1_30
https://doi.org/10.1007/978-3-642-84938-1_30
Publikováno v:
Cancer research. 50(2)
Benzene is an established human leukemogen. Workers occupationally exposed to benzene exhibit increased frequencies of both structural and numerical chromosomal aberrations in their peripheral blood lymphocytes. The metabolite(s) responsible for thes
Autor:
J D, Tucker, D A, Eastmond
Publikováno v:
Progress in clinical and biological research.