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Publikováno v:
Bioorganicheskaia khimiia. 16(3)
Five angiotensin cycloanalogues have been synthesised by classical methods of peptide chemistry, cyclisation being carried out via pentafluorophenyl esters. Cycloanalogues (I-IV) with a fixed potential turn in the C-terminal part of the angiotensin m
Publikováno v:
Bioorganicheskaia khimiia. 12(8)
The synthesis and biological properties of 10 angiotensin cyclic analogues are described. These compounds exhibit prolong depressor effects and act as potent histamine-releasing agents.