Zobrazeno 1 - 10
of 136
pro vyhledávání: '"D A, Basketter"'
Autor:
R. Roggeband, Marco Corvaro, Hans Bender, D. A. Basketter, Jim Bridges, F. Lamplmair, Boris P. Müller, Silvia Casati, A. Irizar, Petra S. Kern, Laura H. Rossi, Sonja Beken, S. Cuvellier, Irene Manou, Miriam N. Jacobs, Bruno Hubesch
Publikováno v:
Regulatory Toxicology and Pharmacology. 117:104767
Skin sensitising substances that induce contact allergy and consequently risk elicitation of allergic contact dermatitis (ACD) remain an important focus regarding the replacement of animal experimentation. Current in vivo methods, notably the local l
Publikováno v:
Human & Experimental Toxicology. 34:1222-1230
Skin sensitization associated with allergic contact dermatitis is a common health problem and is an important consideration for toxicologists in safety assessment. Historically, in vivo predictive tests have been used with good success to identify su
Publikováno v:
British Journal of Dermatology. 168:692-699
The skin immune system's propensity to produce allergic contact dermatitis (ACD) to harmless chemicals, while otherwise being an efficient defence system, represents a dermatological paradox. We postulate that a major role in signalling in ACD is pla
Autor:
Ian Kimber, Cindy A. Ryan, David W. Roberts, Grace Patlewicz, Petra S. Kern, Rebecca J. Dearman, D. A. Basketter, G. F. Gerberick, A O Aptula, Eugenio Uriarte
Publikováno v:
SAR and QSAR in Environmental Research. 18:515-541
Skin sensitisation potential is an endpoint that needs to be assessed within the framework of existing and forthcoming legislation. At present, skin sensitisation hazard is normally identified using in vivo test methods, the favoured approach being t
Autor:
Alessandra Gennari, B. Jean Meade, Andrea Cavani, Ian Kimber, Valérie Zuang, Françoise Rousset, D. A. Basketter, Silvia Casati, Gilles Rubinstenn, Federica Sallusto, Pierre Aeby, Peter Griem, Marc Pallardy, Geert R. Verheyen, Nathalie Rougier, Jean Pierre Lepoittevin, G. Frank Gerberick, Thomas Hartung
Publikováno v:
Alternatives to Laboratory Animals. 33:47-62
Preface This is the report of the fifty-first of a series of workshops organised by the European Centre for the Validation of Alternative Methods (ECVAM). The main objective of ECVAM, as defined in 1993 by its Scientific Advisory Committee, is to pro
Publikováno v:
Contact Dermatitis. 51:241-254
Allergic contact dermatitis following the use of hair dyes is well known. Many chemicals are used in hair dyes and it is unlikely that all cases of hair dye allergy can be diagnosed by means of patch testing with p-phenylenediamine (PPD). The objecti
Autor:
A. M. Wolfreys, D. A. Basketter
Publikováno v:
Journal of Toxicology: Cutaneous and Ocular Toxicology. 23:197-205
For some years, those involved with the safety assessment of chemicals have in one way or another considered the degree to which data on either skin sensitization potential or on carcinogenicity may inform them on the other endpoint for a particular
Autor:
D. A. Basketter, G. F. Gerberick, Ian Kimber, M Butler, C Newsome, A. Gamer, W. Steiling, H.-W. Vohr, J.-L. Garrigue
Publikováno v:
Food and Chemical Toxicology. 41:1799-1809
It is clear that contact allergens vary substantially with regard to the relative potency with which they are able to induce skin sensitisation. Considerations of potency will in the future become a significant factor in the classification of skin se
Publikováno v:
Clinical and Experimental Dermatology. 28:177-183
Chemical reactivity plays the driving role in the biological processes that result in the induction of allergic contact dermatitis. This paper presents an overview of the chemical basis of allergic contact dermatitis, including the physicochemical pa