Dual-Pharmacophore Pyrithione-Containing Cephalosporins Kill Both Replicating and Nonreplicating Mycobacterium tuberculosis .

Autor: Lopez Quezada L; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States., Li K; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States., McDonald SL; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States., Nguyen Q; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States., Perkowski AJ; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States., Pharr CW; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States., Gold B; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States., Roberts J; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States., McAulay K; Center for Global Health , Weill Cornell Medicine , 402 East 67th Street , New York , New York 10065 , United States.; Les Centres GHESKIO , 33, Boulevard Harry Truman , Port-au-Prince , Haiti., Saito K; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States., Somersan Karakaya S; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States., Javidnia PE; Department of Medicine , Weill Cornell Medical College , New York , New York 10065 , United States., Porras de Francisco E; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain., Amieva MM; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain., Dı Az SP; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain., Mendoza Losana A; Diseases of the Developing World (DDW), Tres Cantos Medicine Development Campus , GlaxoSmithKline , Severo Ochoa 2 , Tres Cantos , Madrid 28760 , Spain., Zimmerman M; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States., Liang HH; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States., Zhang J; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States., Dartois V; Public Health Research Institute, New Jersey Medical School , Rutgers, the State University of New Jersey , 225 Warren Street , Newark , New Jersey 07013 , United States., Sans S; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France., Lagrange S; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France., Goullieux L; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France., Roubert C; Evotec ID (Lyon), SAS , 1541, Avenue Marcel Merieux , Marcy l'Etoile 69280 , France., Nathan C; Department of Microbiology and Immunology , Weill Cornell Medicine , 1300 York Avenue , New York , New York 10065 , United States., Aubé J; Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy , University of North Carolina at Chapel Hill , 125 Mason Farm Road , Chapel Hill , North Carolina 27599 , United States.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2019 Aug 09; Vol. 5 (8), pp. 1433-1445. Date of Electronic Publication: 2019 Jun 11.