Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Dörthe Masemann"'
Autor:
Maurice Krause, Gilbert Greefrath, Boris Forthmann, Fabienne E. Kremer, Felix Reer, Daniel Laumann, Dörthe Masemann, Cornelia Denz, Susanne Heinicke, Barbara Leibrock, Annette Marohn, Thorsten Quandt, Elmar Souvignier, Malte Ubben, Stefan Heusler
Publikováno v:
Frontiers in Education, Vol 9 (2024)
IntroductionNowadays, more and more digital resources are used in modern mathematical modeling classes. In order to access these resources, students need a suitable digital device—often mobile devices are used for this purpose. There are several co
Externí odkaz:
https://doaj.org/article/b5eaf0745bb04334937481eb0085bfd8
Autor:
Ramona Meissner, Viktor Wixler, Franziska Paulina Wulfert, Jasmin Carina Jacob, Benjamin G. Hale, Thomas Robeck, Dörthe Masemann, Yvonne Boergeling, Stephan Ludwig
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100741- (2023)
Low pathogenic influenza A viruses (IAVs) have shown promising oncolytic potential in lung cancer–bearing mice. However, as replication-competent pathogens, they may cause side effects in immunocompromised cancer patients. To circumvent this proble
Externí odkaz:
https://doaj.org/article/e049391d1543496e91f84abf9feb0076
Autor:
Verónica A. Ferrando, Marcel E. Friedrich, Shrey Gandhi, Alexander Mellmann, Dörthe Masemann, Anmari Christersson, Darisuren Anhlan, Linda Brunotte, Monika Stoll, Timm Harder, Martin Beer, Yvonne Boergeling, Stephan Ludwig
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTInfluenza A viruses (IAV) cause annual epidemics and occasional pandemics in humans. The most recent pandemic outbreak occurred in 2009 with H1N1pdm09. This virus, which most likely reassorted in swine before its transmission to humans, was r
Externí odkaz:
https://doaj.org/article/4a0d20eb3cce4efea4caca01d4f9af78
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 190-204 (2020)
Recently, we showed that infection of primary lung tumor-bearing mice with oncolytic influenza A viruses (IAVs) led to strong virus-induced tumor cell lysis but also to restoration of immune competence of innate immune cells. Murine B16-F10 melanoma
Externí odkaz:
https://doaj.org/article/d458c465ae544720b1c71af883fcb757
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
We investigated the role of IAV nonstructural protein 1 NS1 in host gene shutoff—a central feature of IAV replication. We demonstrate that the effector domain of NS1 alone mediates host gene shutoff by inhibition of host transcription and by deregu
Externí odkaz:
https://doaj.org/article/0509ccc9b9db4d26bb5326552b329648
Autor:
Dörthe Masemann, Ramona Meissner, Tanja Schied, Brian D Lichty, Ulf R Rapp, Viktor Wixler, Stephan Ludwig
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Non-small cell lung cancers (NSCLCs) establish a highly immunosuppressive tumor microenvironment supporting cancer growth. To interfere with cancer-mediated immunosuppression, selective immune-checkpoint inhibitors (ICIs) have been approved as a stan
Externí odkaz:
https://doaj.org/article/a9f07968906048c0afdd69db5a883213
Autor:
Dörthe Masemann, Katharina Köther, Meike Kuhlencord, Georg Varga, Johannes Roth, Brian Dennis Lichty, Ulf Rüdiger Rapp, Viktor Wixler, Stephan Ludwig
Publikováno v:
OncoImmunology, Vol 7, Iss 5 (2018)
Non-small-cell lung cancer (NSCLC) is the most frequent type of lung cancer and demonstrates high resistance to radiation and chemotherapy. These tumors evade immune system detection by promoting an immunosuppressive tumor microenvironment. Genetic a
Externí odkaz:
https://doaj.org/article/7978c9ea44a246c99fae503377d470fc
Autor:
Izabella T Silva, Annelise Carvalho, Karen L Lang, Sabine E Dudek, Dörthe Masemann, Fernando J Durán, Miguel S B Caro, Ulf R Rapp, Viktor Wixler, Eloir P Schenkel, Cláudia M O Simões, Stephan Ludwig
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117794 (2015)
Lung cancer is the most deadly type of cancer in humans, with non-small-cell lung cancer (NSCLC) being the most frequent and aggressive type of lung cancer showing high resistance to radiation and chemotherapy. Despite the outstanding progress made i
Externí odkaz:
https://doaj.org/article/229051bf1cf8454caca58ab6e36010c1
Autor:
Tanja Schied, Dörthe Masemann, Viktor Wixler, Yvonne Boergeling, Veronika Lührmann, Igor Z. Zaytsev, Stephan Ludwig, Georg Varga, Rafael Leite Dantas
Publikováno v:
Mol Ther
The major challenge in the treatment of autoimmune diseases is the restoration of the impaired peripheral immune tolerance that always accompanies the development of such diseases. Here, we show that small splenic peptides (SSPs) of whole spleen extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d20aeaa96e245b3e18fb21d79fef8de
https://doi.org/10.1016/j.ymthe.2021.08.030
https://doi.org/10.1016/j.ymthe.2021.08.030
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
Host shutoff in influenza A virus (IAV) infection is a key process contributing to viral takeover of the cellular machinery and resulting in the downregulation of host gene expression. Analysis of nascently transcribed RNA in a cellular model that al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede2a47a33100a6cc9be8935fbadd9a9
http://europepmc.org/articles/PMC8546537
http://europepmc.org/articles/PMC8546537