Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling

Autor: Phoa, Athena F., Browne, Stephen, Gurgis, Fadi M.S., Åkerfeldt, Mia C., Döbber, Alexander, Renn, Christian, Peifer, Christian, Stringer, Brett W., Day, Bryan W., Wong, Chin, Chircop, Megan, Johns, Terrance G., Kassiou, Michael, Munoz, Lenka

Publikováno v: In Biochemical Pharmacology 15 December 2015 98(4):587-601

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Photoaktivierbare Kinase- und Tubulininhibitoren

Autor: Döbber, Alexander

The idea of using light to control biological activity of highly potent drugs like kinase inhibitors or microtubule-targeting agents both temporal and spatial became an appealing strategy to tackle selectivity related issues such as severe side-effec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::481f3d5bf8e71247cd10029f21de6719
https://macau.uni-kiel.de/receive/dissertation_diss_00023688

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Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent.

Autor: Döbber A; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia.; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Phoa AF; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia., Abbassi RH; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia., Stringer BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia., Day BW; QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD 4006, Australia., Johns TG; Oncogenic Signalling Laboratory and Brain Cancer Discovery Collaborative, Centre for Cancer Research, Hudson Institute of Medical Research, 27-31 Wright Street, Clayton, VIC 3168, Australia.; Monash University, Wellington Road, Clayton, VIC 3800, Australia., Abadleh M; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Peifer C; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, 24118 Kiel, Germany., Munoz L; School of Medical Sciences and Charles Perkins Centre, The University of Sydney, Sydney, NSW 2006, Australia.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2017 Mar 15; Vol. 8 (4), pp. 395-400. Date of Electronic Publication: 2017 Mar 15 (Print Publication: 2017).