Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Dóra Payer-Lengyel"'
Autor:
Istvan Gyertyan, Bela Kiss, György Szabó, Mónika Vastag, Eva Hegyi, Dóra Payer-Lengyel, Krisztina Vukics, Attila Szemzö, Judit Szikra, Judit Laszy, Janos Fischer, Peter Erdelyi, Balázs Varga
Publikováno v:
Journal of Medicinal Chemistry. 52:4329-4337
Obesity is a major clinical problem in the western world, and many molecular targets have been explored in the search for effective therapeutic agents. One of these, antagonism of the cannabinoid 1 (CB1) receptor, rose to prominence following reports
Autor:
Krisztina Vukics, György M. Keserű, Dóra Payer-Lengyel, Janos Fischer, Andrea Baki, Judit Szikra, György Szabó, László Molnár, Róbert Gábor Kiss
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(13)
Hit-to-lead optimization of a novel series of N-alkyl-N-[2-oxo-2-(4-aryl-4H-pyrrolo[1,2-a]quinoxaline-5-yl)-ethyl]-carboxylic acid amides, derived from a high throughput screening (HTS) hit, are described. Subsequent optimization led to identificatio